Nature Search

Reductive cyanation of organic chlorides using CO₂ and NH₃ via Triphos–Ni(I) species

Nitriles are key intermediates in production of pharmaceuticals, agrochemicals and organic materials. Here, the authors report a nickel-catalyzed reductive cyanation of organic chlorides with CO₂/NH₃ and urea as cyanation reagents to afford a broad range of organic nitriles.

Yanan Dong
Peiju Yang
Yuehui Li
ResearchOpen Access14 Aug 2020
Nature Communications

Volume: 11, P: 1-9
Disparities in high fasting plasma glucose-related cardiovascular disease burden in China

Evidence for comprehensive assessment of cardiovascular disease (CVD) burden attributable to high fasting plasma glucose (FPG) in China is limited. Here, the authors show CVD deaths attributable to high FPG varied substantially across China. Exposure to high FPG and population aging were the primary drivers of increased CVD burden.

Xue Cao
Yixin Tian
Zengwu Wang
ResearchOpen Access11 Oct 2024
Nature Communications

Volume: 15, P: 1-10
Multiplexed transcriptomic profiling of the fate of human CAR T cells in vivo via genetic barcoding with shielded small nucleotides

A cell-barcoding method leveraging ubiquitous promoters to express small-RNA barcodes modified with direct-capture sequences allows for the longitudinal tracking of the transcriptional states of CAR T cells infused in a mouse model of leukaemia.

Xiaoyin Lu
Shane M. Lofgren
Pawel K. Mazur
Research31 Aug 2023
Nature Biomedical Engineering

Volume: 7, P: 1170-1187
Deep phenotyping unveils hidden traits and genetic relations in subtle mutants

Experimenter scoring of cellular imaging data can be biased. This study describes an automated and unbiased multidimensional phenotyping method that relies on machine learning and complex feature computation of imaging data, and identifies weak alleles affecting synapse morphology in live C. elegans.

Adriana San-Miguel
Peri T. Kurshan
Hang Lu
ResearchOpen Access23 Nov 2016
Nature Communications

Volume: 7, P: 1-13
Relationship among ultrasound features, pus Mycobacterium tuberculosis load, and efficacy of antituberculosis drugs in patients with necrotizing tuberculous lymphadenitis

Ying Zhang
Ting Lin
Gaoyi Yang
ResearchOpen Access06 Dec 2024
Scientific Reports

Volume: 14, P: 1-10
Influence of heat pipe layout parameters on the cooling effect of spontaneous combustion coal gangue dumps

Jiamin Tong
Yongbo Zhang
Yuehui Zhang
ResearchOpen Access07 Nov 2024
Scientific Reports

Volume: 14, P: 1-23
Genome-wide comparative analyses reveal selection signatures underlying adaptation and production in Tibetan and Poll Dorset sheep

Yingyue Zhang
Xianglan Xue
Qianjun Zhao
ResearchOpen Access28 Jan 2021
Scientific Reports

Volume: 11, P: 1-12
FOPID controller design for pneumatic control valves with ultra-low overshoot, rapid response and enhanced robustness

Yuxin He
Aixiang Ma
Sihai Zhao
ResearchOpen Access06 Feb 2025
Scientific Reports

Volume: 15, P: 1-24
Skin transcriptome reveals the intrinsic molecular mechanisms underlying hair follicle cycling in Cashmere goats under natural and shortened photoperiod conditions

Min Yang
Shen Song
Lin Jiang
ResearchOpen Access18 Oct 2017
Scientific Reports

Volume: 7, P: 1-12
Expression profiling and functional characterization of miR-192 throughout sheep skeletal muscle development

Qian Zhao
Ye Kang
Qian-Jun Zhao
ResearchOpen Access25 Jul 2016
Scientific Reports

Volume: 6, P: 1-12
CD22 CAR T-cell therapy in refractory or relapsed B acute lymphoblastic leukemia

Jing Pan
Qing Niu
Chunrong Tong
ResearchOpen Access20 May 2019
Leukemia

Volume: 33, P: 2854-2866
Genome-wide detection of copy number variation in Chinese indigenous sheep using an ovine high-density 600 K SNP array

Qing Ma
Xuexue Liu
Lin Jiang
ResearchOpen Access19 Apr 2017
Scientific Reports

Volume: 7, P: 1-10
Genomic analysis identified a potential novel molecular mechanism for high-altitude adaptation in sheep at the Himalayas

Neena Amatya Gorkhali
Kunzhe Dong
Yuehui Ma
ResearchOpen Access22 Jul 2016
Scientific Reports

Volume: 6, P: 1-10
Identification of selection signals by large-scale whole-genome resequencing of cashmere goats

Xiaokai Li
Rui Su
Jinquan Li
ResearchOpen Access09 Nov 2017
Scientific Reports

Volume: 7, P: 1-10
Edoxaban for stroke prevention in atrial fibrillation and factors associated with dosing: patient characteristics from the prospective observational ETNA-AF-China registry

Xueyuan Guo
Juan Du
Jian Zhang
ResearchOpen Access02 Feb 2024
Scientific Reports

Volume: 14, P: 1-15
Corticosteroids do not influence the efficacy and kinetics of CAR-T cells for B-cell acute lymphoblastic leukemia

Shuangyou Liu
Biping Deng
Chunrong Tong
CorrespondenceOpen Access06 Feb 2020
Blood Cancer Journal

Volume: 10, P: 1-4

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Reductive cyanation of organic chlorides using CO₂ and NH₃ via Triphos–Ni(I) species

Disparities in high fasting plasma glucose-related cardiovascular disease burden in China

Multiplexed transcriptomic profiling of the fate of human CAR T cells in vivo via genetic barcoding with shielded small nucleotides

Deep phenotyping unveils hidden traits and genetic relations in subtle mutants

Relationship among ultrasound features, pus Mycobacterium tuberculosis load, and efficacy of antituberculosis drugs in patients with necrotizing tuberculous lymphadenitis

Influence of heat pipe layout parameters on the cooling effect of spontaneous combustion coal gangue dumps

Genome-wide comparative analyses reveal selection signatures underlying adaptation and production in Tibetan and Poll Dorset sheep

FOPID controller design for pneumatic control valves with ultra-low overshoot, rapid response and enhanced robustness

Skin transcriptome reveals the intrinsic molecular mechanisms underlying hair follicle cycling in Cashmere goats under natural and shortened photoperiod conditions

Expression profiling and functional characterization of miR-192 throughout sheep skeletal muscle development

CD22 CAR T-cell therapy in refractory or relapsed B acute lymphoblastic leukemia

Genome-wide detection of copy number variation in Chinese indigenous sheep using an ovine high-density 600 K SNP array

Genomic analysis identified a potential novel molecular mechanism for high-altitude adaptation in sheep at the Himalayas

Identification of selection signals by large-scale whole-genome resequencing of cashmere goats

Edoxaban for stroke prevention in atrial fibrillation and factors associated with dosing: patient characteristics from the prospective observational ETNA-AF-China registry

Corticosteroids do not influence the efficacy and kinetics of CAR-T cells for B-cell acute lymphoblastic leukemia

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