Axon regeneration is controlled by both positive and negative regulators. In this study, Qin et al. show that KLF4 acts as an intrinsic inhibitor of axon regeneration by antagonizing the cytokine JAK–STAT3 pathway, and that deletion of KLF4 can greatly enhance cytokine-induced axon regeneration.
- Song Qin
- Yuhua Zou
- Chun-Li Zhang
