Nature Search

Characterization of the Microstructure of Poly(propylene oxide)–Segmented Polyamide and Its Suppression of Platelet Adhesion

Nobuhiko Yui
Junko Tanaka
Yasuhisa Sakurai
Research01 Feb 1984
Polymer Journal

Volume: 16, P: 119-128
Surface Properties of Polypropylene Films as Biomaterials

Nobuhiko Yui
Yorito Suzuki
Minoru Terano
Research01 Jun 1995
Polymer Journal

Volume: 27, P: 614-622
Mitochondrial complexity is regulated at ER-mitochondria contact sites via PDZD8-FKBP8 tethering

How PDZD8 acted in Mitochondria-ER contact formation was unclear. Here, the authors show that binding to mitochondrial FKBP8 slows PDZD8’s rapid motion, enhancing contacts and mitochondrial complexity.

Koki Nakamura
Saeko Aoyama-Ishiwatari
Yusuke Hirabayashi
ResearchOpen Access17 Apr 2025
Nature Communications

Volume: 16, P: 1-23
A common deletion at BAK1 reduces enhancer activity and confers risk of intracranial germ cell tumors

Intracranial germ cell tumors (IGCTs) are rare brain tumors mainly diagnosed in children and young adults. Here, the authors conduct a genome-wide association study for IGCTs, identify a risk locus at BAK1, and characterize its functional consequences.

Kyuto Sonehara
Yui Kimura
Keita Terashima
ResearchOpen Access02 Aug 2022
Nature Communications

Volume: 13, P: 1-9
Accuracy of cephalometric landmark and cephalometric analysis from lateral facial photograph by using CNN-based algorithm

Yui Shimamura
Chie Tachiki
Yasushi Nishii
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-15
Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease

Targeting gluten antigens presents a plausible therapy option for celiac disease. Here the authors generate and characterize a broadly neutralizing antibody recognizing more than 25 gluten peptide:HLA-DQ2.5 complexes, with structural analyses implicating its mode of interaction, and with mouse in vivo studies supporting its therapeutic feasibility.

Yuu Okura
Yuri Ikawa-Teranishi
Tomoyuki Igawa
ResearchOpen Access22 Dec 2023
Nature Communications

Volume: 14, P: 1-15
Preoperative prediction of sinonasal papilloma by artificial intelligence using nasal video endoscopy: a retrospective study

Ryosuke Yui
Masahiro Takahashi
Hiromi Kojima
ResearchOpen Access02 Aug 2023
Scientific Reports

Volume: 13, P: 1-7
Simulating metabolic pathways to enhance interpretations of metabolome genome-wide association studies

Shun Kodate
Mitsuharu Sato
Kengo Kinoshita
ResearchOpen Access16 May 2025
Scientific Reports

Volume: 15, P: 1-11
Wnt5a induces renal AQP2 expression by activating calcineurin signalling pathway

The water channel AQP2 mediates the concentration of urine in the kidney. Here Ando et al. show that Wnt5 promotes collecting duct permeability by regulating AQP2 expression and localization through activation of the calmodulin/calcineurin signalling pathway.

Fumiaki Ando
Eisei Sohara
Shinichi Uchida
ResearchOpen Access28 Nov 2016
Nature Communications

Volume: 7, P: 1-12
Mechanisms of D1/D2-like dopaminergic agonist, rotigotine, on lower urinary tract function in rat model of Parkinson’s disease

Mifuka Ouchi
Takeya Kitta
Nobuo Shinohara
ResearchOpen Access16 Mar 2022
Scientific Reports

Volume: 12, P: 1-8
Mechanism of delayed seed germination caused by high temperature during grain filling in rice (Oryza sativa L.)

Chetphilin Suriyasak
Yui Oyama
Yushi Ishibashi
ResearchOpen Access15 Oct 2020
Scientific Reports

Volume: 10, P: 1-11
Bladder outlet obstruction disrupts circadian bladder function in mice

Takeya Kitta
Hiroki Chiba
Nobuo Shinohara
ResearchOpen Access14 Jul 2020
Scientific Reports

Volume: 10, P: 1-7
Profiling of runs of homozygosity from whole-genome sequence data in Japanese biobank

Aye Ko Ko Minn
Motomichi Matsuzaki
Gen Tamiya
ResearchOpen Access03 Apr 2025
Journal of Human Genetics

Volume: 70, P: 287-296
Ionizing radiation triggers the release of mitochondrial DNA into the cytosol as a signal of mitochondrial damage

Tsutomu Shimura
Yui Takahashi
Akira Ushiyama
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-12
Inferring historical survivals of climate relicts: the effects of climate changes, geography, and population-specific factors on herbaceous hydrangeas

Shota Sakaguchi
Yui Asaoka
Hiroaki Setoguchi
Research28 Jan 2021
Heredity

Volume: 126, P: 615-629
Scalable fabrication of graphene nanoribbon quantum dot devices with stable orbital-level spacing

Graphene nanoribbons can be used as quantum dot devices, but scalable fabrication methods are needed. Here, a nanobar technique is used to synthesize graphene nanoribbon-based quantum dot devices with a 56 % yield and stable orbital level splitting up to 20 K.

Toshiaki Kato
Takahito Kitada
Tomohiro Otsuka
ResearchOpen Access22 Dec 2022
Communications Materials

Volume: 3, P: 1-7
Effects of the timing of acute mulberry leaf extract intake on postprandial glucose metabolism in healthy adults: a randomised, placebo-controlled, double-blind study

Masaki Takahashi
Yui Mineshita
Shigenobu Shibata
ResearchOpen Access17 Jan 2023
European Journal of Clinical Nutrition

Volume: 77, P: 468-473
Impact of microgravity and lunar gravity on murine skeletal and immune systems during space travel

Yui Okamura
Kei Gochi
Satoru Takahashi
ResearchOpen Access20 Nov 2024
Scientific Reports

Volume: 14, P: 1-14
The biochemical basis for thermoregulation in heat-producing flowers

Yui Umekawa
Roger S. Seymour
Kikukatsu Ito
ResearchOpen Access20 Apr 2016
Scientific Reports

Volume: 6, P: 1-7
Interchangeable binding of Bcl10 to TRAF2 and cIAPs regulates apoptosis signaling

Daishi Yui
Takunari Yoneda
Masaya Tohyama
Research19 Jul 2001
Oncogene

Volume: 20, P: 4317-4323
Synthetic zwitterions as efficient non-permeable cryoprotectants

Zwitterionic solutions have potential applications as cryoprotectants, but the relationship between structure and performance is underexplored. Here a family of zwitterions are assessed in terms of cytotoxicity, cryopreservation performance, and effect on cell volume and water content.

Yui Kato
Takuya Uto
Kosuke Kuroda
ResearchOpen Access28 Oct 2021
Communications Chemistry

Volume: 4, P: 1-10
Association of cardiovascular disease risk and changes in renin levels by mineralocorticoid receptor antagonists in patients with primary aldosteronism

Regarding Japanese primary aldosteronism, the low, intermediate, and high renin change groups (classified based on the response of renin to mineralocorticoid antagonist treatment) had CVD incidence of 2.1%, 0.5%, and 3.7%, respectively, during the 5-year study period.

Motoko Nomura
Isao Kurihara
Chiba Yoshiro
Research28 Jun 2022
Hypertension Research

Volume: 45, P: 1476-1485
Identification of a prostaglandin D₂ metabolite as a neuritogenesis enhancer targeting the TRPV1 ion channel

Takahiro Shibata
Katsuhiro Takahashi
Koji Uchida
ResearchOpen Access16 Feb 2016
Scientific Reports

Volume: 6, P: 1-11
Endothelial ROBO4 suppresses PTGS2/COX-2 expression and inflammatory diseases

ROBO4 suppresses PTGS2/COX-2 expression by inhibiting prolonged RAC1 activation in endothelial cells, ameliorating inflammatory diseases in mice; these endothelial molecules represent potential therapeutic targets for inflammatory diseases.

Masato Tanaka
Keisuke Shirakura
Yoshiaki Okada
ResearchOpen Access18 May 2024
Communications Biology

Volume: 7, P: 1-11
Cephalometric landmark detection without X-rays combining coordinate regression and heatmap regression

Kaisei Takahashi
Yui Shimamura
Masafumi Hagiwara
ResearchOpen Access16 Nov 2023
Scientific Reports

Volume: 13, P: 1-13
Cell-compatible isotonic freezing media enabled by thermo-responsive osmolyte-adsorption/exclusion polymer matrices

Non-cell-permeable cryoprotectants exhibit cryopreserving effects by preventing intracellular ice crystal formation, but these can damage cells due to high osmotic pressure and dehydration. Here, the authors developed a poly(zwitterion) isotonic cryoprotectant that forms a firm matrix around cells that prevents the influx of ice crystal nuclei without the need for high osmotic pressure and dehydration.

Yui Kato
Yuya Matsuda
Kosuke Kuroda
ResearchOpen Access29 Nov 2023
Communications Chemistry

Volume: 6, P: 1-10
α-1,3-Glucanase from the gram-negative bacterium Flavobacterium sp. EK-14 hydrolyzes fungal cell wall α-1,3-glucan

Masaki Takahashi
Shigekazu Yano
Susumu Kokeguchi
ResearchOpen Access05 Dec 2023
Scientific Reports

Volume: 13, P: 1-12
Publisher Correction: Cretaceous amber fossils highlight the evolutionary history and morphological conservatism of land snails

Takahiro Hirano
Kaito Asato
Satoshi Chiba
Amendments and CorrectionsOpen Access09 Dec 2019
Scientific Reports

Volume: 9, P: 1
Lunar gravity prevents skeletal muscle atrophy but not myofiber type shift in mice

Artificial lunar gravity is shown to be sufficient to suppress microgravity-induced soleus muscle atrophy but not myofiber type shift in mice.

Takuto Hayashi
Ryo Fujita
Satoru Takahashi
ResearchOpen Access21 Apr 2023
Communications Biology

Volume: 6, P: 1-10
Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids

Inoue et al develop a non-invasive method of analyzing human skin mRNA using RNA in skin surface lipids collected with oil-blotting films. The authors outline the validation of this methodology and describe an application to determine transcriptome in skin surface lipids in patients with atopic dermatitis versus healthy skin.

Takayoshi Inoue
Tetsuya Kuwano
Takatoshi Murase
ResearchOpen Access09 Mar 2022
Communications Biology

Volume: 5, P: 1-13
Factors associated with the surgical outcomes of Baerveldt glaucoma implant for open-angle glaucoma, an age-related eye disease

Satoshi Iraha
Yuji Takihara
Toshihiro Inoue
ResearchOpen Access25 Jan 2022
Scientific Reports

Volume: 12, P: 1-9
Elderly patients with suspected Charcot-Marie-Tooth disease should be tested for the TTR gene for effective treatments

Takaki Taniguchi
Masahiro Ando
Hiroshi Takashima
Research14 Jan 2022
Journal of Human Genetics

Volume: 67, P: 353-362
Diverse pathological lesions of primary aldosteronism and their clinical significance

Koshiro Nishimoto
Hironobu Umakoshi
Chiba Yoshiro
ResearchOpen Access12 Jan 2021
Hypertension Research

Volume: 44, P: 498-507
Non-aqueous, zwitterionic solvent as an alternative for dimethyl sulfoxide in the life sciences

Dimethyl sulfoxide is a commonly used solvent, but its permeability and effect on cells is problematic. Here, an alternative solvent, a zwitterion-type ionic liquid, and its plasma membrane affinity as well as cryo-protecting property and drug-dissolution ability are reported.

Kosuke Kuroda
Tetsuo Komori
Eishu Hirata
ResearchOpen Access11 Nov 2020
Communications Chemistry

Volume: 3, P: 1-7
Historical changes and between-facility differences in adrenal venous sampling for primary aldosteronism in Japan

Yuichi Fujii
Yoshiyu Takeda
Takahisa Kawaguchi
Research28 Aug 2019
Journal of Human Hypertension

Volume: 34, P: 34-42
Cretaceous amber fossils highlight the evolutionary history and morphological conservatism of land snails

Takahiro Hirano
Kaito Asato
Satoshi Chiba
ResearchOpen Access04 Nov 2019
Scientific Reports

Volume: 9, P: 1-16
Effects of scavenger receptors-1 class A stimulation on macrophage morphology and highly modified advanced glycation end product-protein phagocytosis

Shinichi Hamasaki
Takuro Kobori
Hideo Takahashi
ResearchOpen Access12 Apr 2018
Scientific Reports

Volume: 8, P: 1-11
Melinjo seed extract increases adiponectin multimerization in physiological and pathological conditions

Kentaro Oniki
Taisei Kawakami
Tsuyoshi Shuto
ResearchOpen Access09 Mar 2020
Scientific Reports

Volume: 10, P: 1-13
Very low-density lipoprotein receptor increases in a liver-specific manner due to protein deficiency but does not affect fatty liver in mice

Yui Oshio
Yuta Hattori
Asako Takenaka
ResearchOpen Access13 Apr 2021
Scientific Reports

Volume: 11, P: 1-11
Age-stratified comparison of clinical outcomes between medical and surgical treatments in patients with unilateral primary aldosteronism

Ryo Nakamaru
Koichi Yamamoto
Daisuke Yabe
ResearchOpen Access25 Mar 2021
Scientific Reports

Volume: 11, P: 1-10
The production of coagulation factor VII by adipocytes is enhanced by tumor necrosis factor-α or isoproterenol

N Takahashi
T Yoshizaki
M Ieko
Research15 Dec 2014
International Journal of Obesity

Volume: 39, P: 747-754

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