Nature Search

Comparison of anti-inflammatory and anti-angiogenic effects of JAK inhibitors in IL-6 and TNFα-stimulated fibroblast-like synoviocytes derived from patients with RA

Yoshihito Suda
Kemmei Ikuta
Tsukasa Matsubara
ResearchOpen Access21 Mar 2025
Scientific Reports

Volume: 15, P: 1-9
Accuracy of cup position following robot-assisted total hip arthroplasty may be associated with surgical approach and pelvic tilt

Shinya Hayashi
Shingo Hashimoto
Ryosuke Kuroda
ResearchOpen Access07 Apr 2021
Scientific Reports

Volume: 11, P: 1-9
Morphological analysis of the distal femur as a surgical reference in biplane distal femoral osteotomy

Shohei Sano
Takehiko Matsushita
Ryosuke Kuroda
ResearchOpen Access27 May 2024
Scientific Reports

Volume: 14, P: 1-8
Combined landscape of single-nucleotide variants and copy number alterations in clonal hematopoiesis

Analysis of single-nucleotide variants and copy number alterations gives a more complete picture of clonal hematopoiesis and its impact on hematological malignancy and cardiovascular disease.

Ryunosuke Saiki
Yukihide Momozawa
Seishi Ogawa
Research08 Jul 2021
Nature Medicine

Volume: 27, P: 1239-1249
Decreased CALM expression reduces Aβ42 to total Aβ ratio through clathrin-mediated endocytosis of γ-secretase

CALM is an adaptor protein required for clathrin-mediated endocytosis, and is a protective factor in Alzheimer’s disease. Here, Kanatsu et al.show that CALM can reduce the production of toxic Aß42 protein by driving clathrin-mediated endocytosis of γ-secretase.

Kunihiko Kanatsu
Yuichi Morohashi
Takeshi Iwatsubo
Research28 Feb 2014
Nature Communications

Volume: 5, P: 1-12
Quadrupole anomalous Hall effect in magnetically induced electron nematic state

The anomalous Hall effect in materials with complex magnetic structures has attracted significant research attention. Here the authors report anisotropic anomalous Hall effect in epitaxial NiCo2O4 films attributed to an extended toroidal quadrupole conical magnetic order.

Hiroki Koizumi
Yuichi Yamasaki
Hideto Yanagihara
ResearchOpen Access08 Dec 2023
Nature Communications

Volume: 14, P: 1-7
Effect of febuxostat on left ventricular diastolic function in patients with asymptomatic hyperuricemia: a sub analysis of the PRIZE Study

Kenya Kusunose
Hisako Yoshida
Mikiko Kagiyama
ResearchOpen Access17 Oct 2021
Hypertension Research

Volume: 45, P: 106-115
A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer

Advanced colorectal cancers are characterised by intra-tumour heterogeneity dictated by neutral evolution. Here the authors analyse early colorectal tumours by whole-exome sequencing and find that Darwinian evolution determines the fate of early lesions in colorectal adenoma and carcinoma in situ.

Tomoko Saito
Atsushi Niida
Koshi Mimori
ResearchOpen Access23 Jul 2018
Nature Communications

Volume: 9, P: 1-11
A variant at 9q34.11 is associated with HLA-DQB1*06:02 negative essential hypersomnia

Taku Miyagawa
Seik-Soon Khor
Katsushi Tokunaga
Research28 Sept 2018
Journal of Human Genetics

Volume: 63, P: 1259-1267
SIRT1 antisense long noncoding RNA attenuates interleukin-1β-induced osteoarthritic gene expression in human chondrocytes through its mRNA interaction

Takeo Tokura
Takehiko Matsushita
Ryosuke Kuroda
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-11
Long-term effects of ipragliflozin on blood pressure in patients with type 2 diabetes: insights from the randomized PROTECT trial

Yuichi Saito
Atsushi Tanaka
Kosuke Nishio
Research14 Nov 2023
Hypertension Research

Volume: 47, P: 168-176
A rare genetic variant in the cleavage site of prepro-orexin is associated with idiopathic hypersomnia

Taku Miyagawa
Susumu Tanaka
Makoto Honda
ResearchOpen Access12 Apr 2022
npj Genomic Medicine

Volume: 7, P: 1-9
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

The number of dendritic spines is reduced in the postmortem brains of individuals with schizophrenia. Revealing a potential mechanism of such change, this study finds that the schizophrenia-associated protein DISC1 regulates the Rho GTPase pathway to modulate dendritic spine size.

Akiko Hayashi-Takagi
Manabu Takaki
Akira Sawa
Research07 Feb 2010
Nature Neuroscience

Volume: 13, P: 327-332
Factors associated with carotid intima-media thickness progression in patients with asymptomatic hyperuricemia: insights from the PRIZE study

Yuichi Saito
Atsushi Tanaka
Mikiko Kagiyama
ResearchOpen Access05 Jul 2023
Scientific Reports

Volume: 13, P: 1-10
An association analysis of HLA-DQB1 with narcolepsy without cataplexy and idiopathic hypersomnia with/without long sleep time in a Japanese population

Taku Miyagawa
Hiromi Toyoda
Katsushi Tokunaga
ResearchOpen Access17 Sept 2015
Human Genome Variation

Volume: 2, P: 1-4
Impact of shear wave elastography and attenuation imaging for predicting life-threatening event in patients with metabolic dysfunction-associated steatotic liver disease

Yudai Fujiwara
Hidekatsu Kuroda
Takayuki Matsumoto
ResearchOpen Access07 Feb 2025
Scientific Reports

Volume: 15, P: 1-10
Susceptibility of cyclin-dependent kinase inhibitor 1-deficient mice to rheumatoid arthritis arising from interleukin-1β-induced inflammation

Yoshinori Takashima
Shinya Hayashi
Ryosuke Kuroda
ResearchOpen Access15 Jun 2021
Scientific Reports

Volume: 11, P: 1-15
Fine-tuning of dopamine receptor signaling with aripiprazole counteracts ketamine’s dissociative action, but not its antidepressant effect

Daiki Nakatsuka
Taro Suwa
Toshiya Murai
ResearchOpen Access08 Mar 2025
Translational Psychiatry

Volume: 15, P: 1-12
Novel USP9X variants in two patients with X-linked intellectual disability

Yoshinori Tsurusaki
Yukiko Kuroda
Kenji Kurosawa
ResearchOpen Access21 Oct 2019
Human Genome Variation

Volume: 6, P: 1-3
Discordant phenotype caused by CASK mutation in siblings with NF1

Hiroaki Murakami
Yuichi Kimura
Kenji Kurosawa
ResearchOpen Access26 Apr 2019
Human Genome Variation

Volume: 6, P: 1-4
Profiling of runs of homozygosity from whole-genome sequence data in Japanese biobank

Aye Ko Ko Minn
Motomichi Matsuzaki
Gen Tamiya
ResearchOpen Access03 Apr 2025
Journal of Human Genetics

Volume: 70, P: 287-296
Synthesis of ultrasmall Li–Mn spinel oxides exhibiting unusual ion exchange, electrochemical and catalytic properties

Yumi Miyamoto
Yoshiyuki Kuroda
Noritaka Mizuno
ResearchOpen Access12 Oct 2015
Scientific Reports

Volume: 5, P: 1-13
Anemia in Patients with Severe Aortic Stenosis

Kazuya Nagao
Tomohiko Taniguchi
Mitsuru Kitano
ResearchOpen Access13 Feb 2019
Scientific Reports

Volume: 9, P: 1-11
Asymptomatic versus Symptomatic Patients with Severe Aortic Stenosis

Norio Kanamori
Tomohiko Taniguchi
Mitsuru Kitano
ResearchOpen Access04 Jul 2018
Scientific Reports

Volume: 8, P: 1-10

Search

Comparison of anti-inflammatory and anti-angiogenic effects of JAK inhibitors in IL-6 and TNFα-stimulated fibroblast-like synoviocytes derived from patients with RA

Accuracy of cup position following robot-assisted total hip arthroplasty may be associated with surgical approach and pelvic tilt

Morphological analysis of the distal femur as a surgical reference in biplane distal femoral osteotomy

Combined landscape of single-nucleotide variants and copy number alterations in clonal hematopoiesis

Decreased CALM expression reduces Aβ42 to total Aβ ratio through clathrin-mediated endocytosis of γ-secretase

Quadrupole anomalous Hall effect in magnetically induced electron nematic state

Effect of febuxostat on left ventricular diastolic function in patients with asymptomatic hyperuricemia: a sub analysis of the PRIZE Study

A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer

A variant at 9q34.11 is associated with HLA-DQB106:02* negative essential hypersomnia

SIRT1 antisense long noncoding RNA attenuates interleukin-1β-induced osteoarthritic gene expression in human chondrocytes through its mRNA interaction

Long-term effects of ipragliflozin on blood pressure in patients with type 2 diabetes: insights from the randomized PROTECT trial

A rare genetic variant in the cleavage site of prepro-orexin is associated with idiopathic hypersomnia

Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

Factors associated with carotid intima-media thickness progression in patients with asymptomatic hyperuricemia: insights from the PRIZE study

An association analysis of HLA-DQB1 with narcolepsy without cataplexy and idiopathic hypersomnia with/without long sleep time in a Japanese population

Impact of shear wave elastography and attenuation imaging for predicting life-threatening event in patients with metabolic dysfunction-associated steatotic liver disease

Susceptibility of cyclin-dependent kinase inhibitor 1-deficient mice to rheumatoid arthritis arising from interleukin-1β-induced inflammation

Fine-tuning of dopamine receptor signaling with aripiprazole counteracts ketamine’s dissociative action, but not its antidepressant effect

Novel USP9X variants in two patients with X-linked intellectual disability

Discordant phenotype caused by CASK mutation in siblings with NF1

Profiling of runs of homozygosity from whole-genome sequence data in Japanese biobank

Synthesis of ultrasmall Li–Mn spinel oxides exhibiting unusual ion exchange, electrochemical and catalytic properties

Anemia in Patients with Severe Aortic Stenosis

Asymptomatic versus Symptomatic Patients with Severe Aortic Stenosis

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