Search

This study demonstrates that tuning the grain boundary density in nanoparticle assemblies by controlling nanoparticle collisions significantly enhances their activity, selectivity, and stability towards electrocatalytic reactions.

The accurate determination of quark mixing parameters is essential for the understanding of the Standard Model. The LHCb collaboration now reports the coupling strength of the b quark to the u quark through the measurement of a baryonic decay mode.

The genome of the model fern species Ceratopteris richardii reveals a history of remarkably dynamic genome evolution, including rapid changes in genome content and structure following the most recent whole-genome duplication approximately 60 million years ago.

Precise adaptation of motor timing is vital in sensorimotor coordination. Here, the authors show that mice can rapidly adjust conditioned eyelid closure between delay and trace eyeblink conditioning, and that this adaptation is dependent on the modulation of medial prefrontal cortex activity.

Analyses of the proportions of individuals who have completed key levels of schooling across all low- and middle-income countries from 2000 to 2017 reveal inequalities across countries as well as within populations.

As electric vehicle batteries adopt cobalt-free layered cathodes to tackle supply chain issues, it greatly impacts battery lifespan. Here, the authors develop a lithium stoichiometry control method to synthesize cobalt-free composite-structured cathodes with high cycling stability, enabling long-life sustainable batteries.

Structure–property relationships between material properties and stem cell behaviour are investigated using high-throughput methods. The data identify the optimal substrates within a range of different polymeric surfaces to support the growth and self-renewal of human embryonic stem cells from fully dissociated single cells.

CP violation has deep implications for particle physics and cosmology. Previously observed only in meson decays, signs of CP violation have now been spotted in baryon decays by analysing the proton–proton collision data from the LHCb detector.

Potassium channels allow vital organ such as brain, heart, and muscles to function. Here, authors reveal the existence of a noncanonical kinematic chain of residues involving the S4/S1 and S1/S5 subunit interfaces that controls the gating of the hERG cardiac channel.

Measurements of the proton’s spin structure in experiments scattering a polarized electron beam off polarized protons in regions of low momentum transfer squared test predictions from chiral effective field theory of the strong interaction.

Spontaneous low-frequency oscillations, which are a feature of biological systems, are challenging to engineer into microrobotic systems. The authors discover a mechanism for asymmetry-induced order and realise electrical and mechanical oscillations in a particle collective to power a microrobotic arm.

Analysis of the optical and γ-ray flux monitoring of the blazar BL Lacertae during its outburst in 2020 shows the existence of quasi-periodic oscillations in the relativistic jet with cycles as short as 13 h.

A hybrid analogue–digital quantum simulator is used to demonstrate beyond-classical performance in benchmarking experiments and to study thermalization phenomena in an XY quantum magnet, including the breakdown of Kibble–Zurek scaling predictions and signatures of the Kosterlitz–Thouless phase transition.

High-density, intrinsically stretchable transistors with high driving ability and integrated circuits with high operation speed and large-scale integration were enabled by a combination of innovations in materials, fabrication process design, device engineering and circuit design.

Genetic screening identifies a rich catalogue of regulators of micronucleus formation.

Two-dimensional transition metal dichalcogenides with peculiar spin–orbit coupling may lead to exotic phenomena. Here, the authors report a large in-plane upper critical field with a two-fold symmetry, suggesting a novel asymmetric spin–orbit coupling in few-layer 1T_d-MoTe₂.

Bennu’s surface has experienced continuous changes, mostly induced by its accelerating spin rate, which could have resulted in a collapse of its interior in the past. This scenario is also supported by the heterogeneity of Bennu’s internal mass distribution.

The fast radio burst FRB 20200120E is shown to originate from a globular cluster in the galaxy M81, and may be a collapsed white dwarf or a merged compact binary star system.

Modules of foldable crystalline silicon solar cells retain their power-conversion efficiency after being subjected to bending stress or exposure to air-flow simulations of a violent storm.

Analyses of single-cell transcriptomic data from patients with VEXAS syndrome combined with xenotransplantation experiments in a mouse model of the disease provide insights on the mechanisms of clonal dominance of mutated cells leading to bone marrow failure

ProBac-seq is a method that uses libraries of DNA probes and commercial microfluidics for single-cell RNA-seq, leveraged here to show heterogeneous gene expression in clonal bacterial cultures including variable toxin expression in an agricultural strain of Clostridium.

Here, the authors introduce a constant light-induced magneto-transport method which seamlessly integrates light, current, and a magnetic field to characterize electron and hole properties across an expansive array of materials.

A proof-of-principle study reports a complete photonic quantum computer architecture that can, once appropriate component performance is achieved, deliver a universal and fault-tolerant quantum computer.

The molecular mechanism of syncytium formation during SARS-CoV-2 infection is not fully understood. Zhang et al. now show that cell surface heparan sulfate enhances spike-induced ACE2 clustering and cell-cell fusion, which depends on a conserved ACE2 linker and is blocked by a heparan sulfate binding drug.

Combining computation and experimentation, the authors reveal prevalent epistatic patterns of the highly diverged B1 β-lactamase family. Both methods locate residues with the strongest epistasis in regions of intermediate residue burial.

A double neutron star merger gave rise to the gravitational-wave event GW 170817, with counterpart electromagnetic radiation in the optical and gamma-ray spectra. Polarization measurements of the optical emission reveal a lanthanide-rich macronova.

In Drosophila, the Calypso–ASX complex catalyzes H2A deubiquitination and aids Polycomb in transcriptional silencing. Here the authors show that the orthologous complex, BAP1.com, promotes gene activation by counteracting PRC1-mediated gene silencing.

By implementing random circuit sampling, experimental and theoretical results establish the existence of transitions to a stable, computationally complex phase that is reachable with current quantum processors.

Nuclear receptors (NR) are drug-responsive master regulators. Here, authors map DNA binding profiles of all human NRs. Their MinSeq Find algorithm identifies masked NR binding sites in genomes and maps ~10% of orphan SNPs linked to numerous diseases.

Phylogenomic analysis of 7,923 angiosperm species using a standardized set of 353 nuclear genes produced an angiosperm tree of life dated with 200 fossil calibrations, providing key insights into evolutionary relationships and diversification.

Confining plasma for fusion requires controlling many parameters. Here the authors report the existence of a narrow parameter space for the simultaneous confinement of energetic alpha particles and removal of slowed-down helium ash in a magnetically confined fusion plasma by using kinetic-magnetohydrodynamic hybrid simulations.

Recently, time-reversal symmetry-breaking charge order was demonstrated in the AV₃Sb₅ (A = K, Rb, Cs) family of kagome superconductors. Here the authors extend this observation to the recently discovered kagome material ScV₆Sn₆ and discuss differences and similarities to other charge-ordered kagome lattices.

The Human Microbiome Project Consortium reports the first results of their analysis of microbial communities from distinct, clinically relevant body habitats in a human cohort; the insights into the microbial communities of a healthy population lay foundations for future exploration of the epidemiology, ecology and translational applications of the human microbiome.

Two-dimensional superconductors will likely have applications not only in devices, but also in the study of fundamental physics. Here, Wang et al. demonstrate the CVD growth of superconducting NbSe2 on a variety of substrates, making these novel materials increasingly accessible.

The authors present a spectrophotometric and hydrodynamical study of supernova OGLE-2014-SN-073, which had remarkably high inferred ejecta mass and energy, potentially higher than can be explained with canonical core-collapse neutrino-driven explosions.

The extent to which mRNA delivery, as well as the cellular response to mRNA drug delivery vehicles, is conserved across species in vivo is unknown. Using species-independent DNA barcoding, the authors measure delivery in humanized, primatized and normal mice, and identify a potential mechanism driving species-dependent lipid nanoparticle delivery.

Gold nanowires conjugated with a cytokine can be transported to specific cells with high precision using electrophoretic and dielectrophoretic forces.

Dengue virus has two membrane proteins, E and M, which undergo dramatic structural changes during the life cycle of the virus. The 3.5-Å cryo-EM structure of the mature prefusion Dengue virion reveals the detailed interactions between E and M, providing insight into how conformational changes are triggered.

Engineered switchgrass and poplar are better feedstocks for biofuel synthesis and yield more biomass in multi-year field trials.

Gene discovery and polygenic predictions from a genome-wide association study of educational attainment in 1.1 million individuals.

Very-high-energy γ-rays observed ten hours after the prompt emission of the γ-ray burst 180720B can be attributed to either an inverse Compton or an extreme synchrotron process.

Detailed mapping of the distribution of water and semiheavy water in the coma of Halley-type comet 12P implies a D/H ratio that is consistent with that of Earth’s water, indicating a common heritage.