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Showing 1–3 of 3 results
Advanced filters: Author: Zengyu Shao Clear advanced filters

  • DIM2-mediated DNA methylation contributes to heterochromatin formation in Neurospora. This study identifies that HP1 protein and the H3K9me3 mark synergistically control DIM2 activity, providing a mechanism for heterochromatin-guided DNA methylation.

    • Zengyu Shao
    • Jiuwei Lu
    • Jikui Song
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • In mammals, de novo DNA methyltransferase DNMT3B is essential for establishing DNA methylation patterns during embryonic development. Here the authors provide a structure-function characterization of homo-oligomeric DNMT3B, revealing the molecular basis for its vulnerability to ICF mutations.

    • Linfeng Gao
    • Yiran Guo
    • Jikui Song
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11