Nature Search

Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population

Xue-Jun Zhang, Zhi-Rong Yao and colleagues report a genome-wide association study for atopic dermatitis in the Chinese Han population. They identified two new susceptibility loci at 5q22 and 20q13.

Liang-Dan Sun
Feng-Li Xiao
Xue-Jun Zhang
Research12 Jun 2011
Nature Genetics

Volume: 43, P: 690-694
GFAT1 promotes the progression of hepatocellular carcinoma via enhancing the O-GlcNAcylation of VEZF1

Jia-yao Yang
Rong Zhang
Kai Wang
ResearchOpen Access26 Aug 2025
Cell Death & Disease

Volume: 16, P: 1-15
An improved LC-MS/MS method for quantitative determination of ilaprazole and its metabolites in human plasma and its application to a pharmacokinetic study

Gan Zhou
Zhi-rong Tan
Han-wu Deng
Research24 Aug 2009
Acta Pharmacologica Sinica

Volume: 30, P: 1330-1336
Renal-targeting triptolide-glucosamine conjugate exhibits lower toxicity and superior efficacy in attenuation of ischemia/reperfusion renal injury in rats

Yu Fu
Qing Lin
Zhi-rong Zhang
Research11 Jul 2016
Acta Pharmacologica Sinica

Volume: 37, P: 1467-1480
Intestinal absorption characteristics of imperialine: in vitro and in situ assessments

Qing Lin
Li-qin Ling
Zhi-rong Zhang
Research08 Jun 2015
Acta Pharmacologica Sinica

Volume: 36, P: 863-873
Absorptive interactions of concurrent oral administration of (+)-catechin and puerarin in rats and the underlying mechanisms

Hui-fang Su
Qing Lin
Zhi-rong Zhang
Research14 Mar 2016
Acta Pharmacologica Sinica

Volume: 37, P: 545-554
Origin of angiosperms and the puzzle of the Jurassic gap

A study reconstructed angiosperm phylogeny on the basis of plastome data representing 2,351 angiosperm and 187 gymnosperm species, and dated the origin of crown angiosperms to be significantly earlier than the estimates based on fossil data.

Hong-Tao Li
Ting-Shuang Yi
De-Zhu Li
Research06 May 2019
Nature Plants

Volume: 5, P: 461-470
Pharmacokinetic interactions between ilaprazole and clarithromycin following ilaprazole, clarithromycin and amoxicillin triple therapy

Shan Cao
Gan Zhou
Wei Zhang
Research23 Jul 2012
Acta Pharmacologica Sinica

Volume: 33, P: 1095-1100
In vitro and in vivo investigation of dexibuprofen derivatives for CNS delivery

Xuan Zhang
Xing Liu
Zhi-rong Zhang
Research03 Feb 2012
Acta Pharmacologica Sinica

Volume: 33, P: 279-288
Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression

The molecular mechanisms underpinning how fasting inhibits tumourigenesis are not completely elucidated. Here, the authors show that fasting upregulates the cholesterogenic gene FDFT1 which leads to decreased AKT/mTOR/HIF1a signalling and glycolysis reduction in colorectal cancer.

Mei-lin Weng
Wan-kun Chen
Chang-hong Miao
ResearchOpen Access20 Apr 2020
Nature Communications

Volume: 11, P: 1-17
Design and evaluation of glomerulus mesangium-targeted PEG-PLGA nanoparticles loaded with dexamethasone acetate

Sha Li
Ying-chun Zeng
Ling Zhang
Research27 Jun 2018
Acta Pharmacologica Sinica

Volume: 40, P: 143-150
Mixed micelles loaded with silybin-polyene phosphatidylcholine complex improve drug solubility

Rui-ling Duan
Xun Sun
Zhi-rong Zhang
Research20 Dec 2010
Acta Pharmacologica Sinica

Volume: 32, P: 108-115
Development of ionic-complex-based nanostructured lipid carriers to improve the pharmacokinetic profiles of breviscapine

Mei Li
Yong Zheng
Zhi-rong Zhang
Research17 Jun 2013
Acta Pharmacologica Sinica

Volume: 34, P: 1108-1115
Soluplus micelles for improving the oral bioavailability of scopoletin and their hypouricemic effect in vivo

Ying-chun Zeng
Sha Li
Zhi-rong Zhang
Research23 Jan 2017
Acta Pharmacologica Sinica

Volume: 38, P: 424-433
Two birds, one stone: dual targeting of the cancer cell surface and subcellular mitochondria by the galectin-3-binding peptide G3-C12

Wei Sun
Lian Li
Yuan Huang
ResearchOpen Access09 Jan 2017
Acta Pharmacologica Sinica

Volume: 38, P: 806-822
Comparison of two methods for tumour-targeting peptide modification of liposomes

Shi-qi Huang
Han-ming Zhang
Ling Zhang
Research21 Oct 2022
Acta Pharmacologica Sinica

Volume: 44, P: 832-840
Thymopentin-loaded phospholipid-based phase separation gel with long-lasting immunomodulatory effects: in vitro and in vivo studies

Ting Zhang
Xian-yan Qin
Zhi-rong Zhang
Research12 Jul 2018
Acta Pharmacologica Sinica

Volume: 40, P: 514-521
PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non-small cell lung cancer by promoting apoptosis via PPARα/AMPK/AKT/FoxO1 pathway

Mei-sa Wang
Qiu-shuang Han
Xuan-sheng Ding
Research26 Mar 2021
Acta Pharmacologica Sinica

Volume: 43, P: 167-176
Decreased left amygdala functional connectivity by cognitive-coping therapy in obsessive-compulsive disorder

Zongya Zhao
Chang-Hong Wang
Xian-Zhang Hu
Research07 May 2021
Molecular Psychiatry

Volume: 26, P: 6952-6962
A novel gemcitabine derivative-loaded liposome with great pancreas-targeting ability

Pei-wen Li
Shi Luo
Ying-chun Zeng
Research23 Apr 2019
Acta Pharmacologica Sinica

Volume: 40, P: 1448-1456
Bioavailability and pharmacokinetic comparison of tanshinones between two formulations of Salvia miltiorrhiza in healthy volunteers

Lu Xing
Zhi-Rong Tan
Hong-Hao Zhou
ResearchOpen Access05 Jul 2017
Scientific Reports

Volume: 7, P: 1-10
Loss of CDH1 (E-cadherin) expression is associated with infiltrative tumour growth and lymph node metastasis

Sun A Kim
Kentaro Inamura
Zhi Rong Qian
ResearchOpen Access07 Jan 2016
British Journal of Cancer

Volume: 114, P: 199-206
Surface loading of nanoparticles on engineered or natural erythrocytes for prolonged circulation time: strategies and applications

Si-qi Zhang
Qiang Fu
Zhen-mi Liu
Reviews26 Mar 2021
Acta Pharmacologica Sinica

Volume: 42, P: 1040-1054

Search

Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population

GFAT1 promotes the progression of hepatocellular carcinoma via enhancing the O-GlcNAcylation of VEZF1

An improved LC-MS/MS method for quantitative determination of ilaprazole and its metabolites in human plasma and its application to a pharmacokinetic study

Renal-targeting triptolide-glucosamine conjugate exhibits lower toxicity and superior efficacy in attenuation of ischemia/reperfusion renal injury in rats

Intestinal absorption characteristics of imperialine: in vitro and in situ assessments

Absorptive interactions of concurrent oral administration of (+)-catechin and puerarin in rats and the underlying mechanisms

Origin of angiosperms and the puzzle of the Jurassic gap

Pharmacokinetic interactions between ilaprazole and clarithromycin following ilaprazole, clarithromycin and amoxicillin triple therapy

In vitro and in vivo investigation of dexibuprofen derivatives for CNS delivery

Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression

Design and evaluation of glomerulus mesangium-targeted PEG-PLGA nanoparticles loaded with dexamethasone acetate

Mixed micelles loaded with silybin-polyene phosphatidylcholine complex improve drug solubility

Development of ionic-complex-based nanostructured lipid carriers to improve the pharmacokinetic profiles of breviscapine

Soluplus micelles for improving the oral bioavailability of scopoletin and their hypouricemic effect in vivo

Two birds, one stone: dual targeting of the cancer cell surface and subcellular mitochondria by the galectin-3-binding peptide G3-C12

Comparison of two methods for tumour-targeting peptide modification of liposomes

Thymopentin-loaded phospholipid-based phase separation gel with long-lasting immunomodulatory effects: in vitro and in vivo studies

PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non-small cell lung cancer by promoting apoptosis via PPARα/AMPK/AKT/FoxO1 pathway

Decreased left amygdala functional connectivity by cognitive-coping therapy in obsessive-compulsive disorder

A novel gemcitabine derivative-loaded liposome with great pancreas-targeting ability

Bioavailability and pharmacokinetic comparison of tanshinones between two formulations of Salvia miltiorrhiza in healthy volunteers

Loss of CDH1 (E-cadherin) expression is associated with infiltrative tumour growth and lymph node metastasis

Surface loading of nanoparticles on engineered or natural erythrocytes for prolonged circulation time: strategies and applications

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