A novel magnetic droplet vaporization strategy was developed for efficient magnetic field-responsive cancer theranostics. Perfluorohexane (PFH)-encapsulated superparamagnetic hollow iron oxide nanoparticles with high magnetic-thermal energy transfer capability quickly respond to external alternating current (a.c.) magnetic field to produce thermal energy and raise the surrounding temperature of tumor tissue. The encapsulated PFH with desirable boiling point of about 56 °C can be vaporized to enhance the ultrasound imaging performance for responsive imaging. Such a magnetic–thermal energy transfer can further completely ablate and remove the tumor against a mice tumor xenograft model.
- Yang Zhou
- Ronghui Wang
- Yuanyi Zheng
