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Scientific Reports (63)
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Showing 101–150 of 201 results

Advanced filters: Author: Zhimin Chen Clear advanced filters

Cytokines as the good predictors of refractory Mycoplasma pneumoniae pneumonia in school-aged children

Yuanyuan Zhang
Shufen Mei
Zhimin Chen
ResearchOpen Access11 Nov 2016
Scientific Reports

Volume: 6, P: 1-6
Hepatic fat content is a determinant of metabolic phenotypes and increased carotid intima-media thickness in obese adults

Huijie Zhang
Zhimin Ma
Xuejun Li
ResearchOpen Access23 Feb 2016
Scientific Reports

Volume: 6, P: 1-7
Species characteristics of lead in sea foods collected from coastal water of Fujian, Southeastern of China

Ye He
Zhiqiang Chen
FengFu Fu
ResearchOpen Access14 Sept 2016
Scientific Reports

Volume: 6, P: 1-8
Relative roles of land- and ocean-atmosphere interactions in Asian-Pacific thermal contrast variability at the precessional band

Yue Wang
ZhiMin Jian
JunMing Chen
ResearchOpen Access06 Jul 2016
Scientific Reports

Volume: 6, P: 1-9
An interpretable machine learning-assisted diagnostic model for Kawasaki disease in children

Mengyu Duan
Zhimin Geng
Gang Yu
ResearchOpen Access07 Mar 2025
Scientific Reports

Volume: 15, P: 1-12
The role of HMOX1-mediated ferroptosis in blue light-induced damage to retinal pigment epithelium

Chunyi Ji
Yiqi Wang
Jing Ji
ResearchOpen Access29 May 2025
Scientific Reports

Volume: 15, P: 1-13
Structure of a Shigella effector reveals a new class of ubiquitin ligases

The IpaH proteins from Shigella show ubiquitin-ligase activity but lack obvious sequence similarity to HECT- or RING-type ubiquitin ligases. The crystal structure of IpaH3 reveals a two-domain protein with HECT-like catalytic activity mapped to a C-terminal domain of novel fold. These findings suggest that IpaH proteins represent a new family of ubiquitin ligases, a conclusion supported by results from a related study by Tyers et al.

Yongqun Zhu
Hongtao Li
Feng Shao
Research09 Nov 2008
Nature Structural & Molecular Biology

Volume: 15, P: 1302-1308
Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA

HIV patients have an increased risk of developing non-AIDS-defining cancers but the molecular mechanisms underlying this predisposition are unclear. Here the authors show that exosomes secreted by HIV-infected T cells or isolated from the blood of HIV-positive patients, stimulate oncogenic properties of cancer cells through the activation of ERK1/2 signaling pathway.

Lechuang Chen
Zhimin Feng
Ge Jin
ResearchOpen Access02 Nov 2018
Nature Communications

Volume: 9, P: 1-12
Senescence-induced p21^high macrophages contributed to CD8⁺ T cells-related immune hyporesponsiveness in kidney transplantation via Zfp36/IL-27 axis

Tingting Zhu
Qixia Shen
Hong Jiang
ResearchOpen Access15 Apr 2025
Cell Discovery

Volume: 11, P: 1-18
Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation

Lu and colleagues find that in response to ionizing radiation, DNA-PK phosphorylates fumarase breaks for local generation of fumarate, which in turn enhances DNA-PK recruitment by inhibiting histone H3 demethylation.

Yuhui Jiang
Xu Qian
Zhimin Lu
Research03 Aug 2015
Nature Cell Biology

Volume: 17, P: 1158-1168
Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis

Phosphofructokinase 1 (PFK1) plays a critical role in glycolysis. Here the authors show that PFK1 platelet isoform is upregulated in Glioblastoma and is required for tumor growth mechanistically, such upregulation is due to an increased stability induced by AKT activation via phosphorylation on residue S386.

Jong-Ho Lee
Rui Liu
Zhimin Lu
ResearchOpen Access16 Oct 2017
Nature Communications

Volume: 8, P: 1-14
Effect of parental migration on the noncognitive abilities of left-behind school-going children in rural China

Babar Nawaz Abbasi
Zhimin Luo
Ali Sohail
ResearchOpen Access06 Jan 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-14
An artificial intelligence-based limited area model for forecasting of surface meteorological variables

The development of an artificial intelligence-based weather forecasting model named YingLong-weather, enables a spatial resolution of 3 km x 3 km and minimises boundary condition issues by smoothing with lateral boundary conditions

Pengbo Xu
Xiaogu Zheng
Xiaoxu Chen
ResearchOpen Access15 May 2025
Communications Earth & Environment

Volume: 6, P: 1-10
Elevated ITGA3 expression serves as a novel prognostic biomarker and regulates tumor progression in cervical cancer

Wei Tan
Gantao Chen
Yanxiang Cheng
ResearchOpen Access07 Nov 2024
Scientific Reports

Volume: 14, P: 1-16
A naturally occurring epiallele associates with leaf senescence and local climate adaptation in Arabidopsis accessions

Epigenetic variation underlies various aspects of phenotypic diversity of plants. Here, He et al show a naturally occurring epiallele controls Arabidopsis leaf senescence by regulating the expression of PHEOPHYTIN PHEOPHORBIDE HYDROLASE (PPH), and is associated with local climate adaptation.

Li He
Wenwu Wu
Jian-Kang Zhu
ResearchOpen Access31 Jan 2018
Nature Communications

Volume: 9, P: 1-11
Cerebellar granule cell replenishment postinjury by adaptive reprogramming of Nestin⁺ progenitors

Recovery of the developing cerebellum after depletion of granule cells, the most plentiful neuron population, depends on adaptive reprogramming of neural progenitors to a new fate and a powerful cell–cell communication system that ensures re-establishment of the correct proportions of different cerebellar cell types and normal circuit formation.

Alexandre Wojcinski
Andrew K Lawton
Alexandra L Joyner
Research14 Aug 2017
Nature Neuroscience

Volume: 20, P: 1361-1370
The draft genome of the fast-growing non-timber forest species moso bamboo (Phyllostachys heterocycla)

Bin Han and colleagues report the draft genome of moso bamboo, an important non-timber forest product. RNA sequencing analysis of bamboo flowering tissues suggests a connection between drought-responsive genes and potential flowering genes.

Zhenhua Peng
Ying Lu
Zehui Jiang
ResearchOpen Access24 Feb 2013
Nature Genetics

Volume: 45, P: 456-461
The feasibility of the ACOSOG Z0011 Criteria to Chinese Breast Cancer Patients: A Multicenter Study

Miao Liu
Shu Wang
Zhigang Yu
ResearchOpen Access16 Oct 2015
Scientific Reports

Volume: 5, P: 1-9
Single-crystalline van der Waals layered dielectric with high dielectric constant

Large-size single-crystal van der Waals layered Bi₂SeO₅ has been synthesized with a high dielectric constant and high breakdown field strength for two-dimensional electronics applications.

Congcong Zhang
Teng Tu
Hailin Peng
Research09 Mar 2023
Nature Materials

Volume: 22, P: 832-837
The IDH1-R132H mutation aggravates cisplatin-induced acute kidney injury by promoting ferroptosis through disrupting NDUFA1 and FSP1 interaction

Kunmei Lai
Zhimin Chen
Yanfang Xu
ResearchOpen Access22 Sept 2024
Cell Death & Differentiation

Volume: 32, P: 242-255
Methylation-modulated PFTK1 regulates gefitinib resistance via Wnt/β-catenin signaling in EGFR mutant non-small-cell lung cancer cells

Highly expressed PFTK1 interacts with LRP6 and activates Wnt/β-catenin signalling to enhance gefitinib resistance in non-small cell lung cancer, and PFTK1 targeting could reverse gefitinib resistance.

Xiaoting Jia
Jingjie Tian
Kai Luo
ResearchOpen Access19 Dec 2024
Communications Biology

Volume: 7, P: 1-12
Integration of metabolomics and transcriptomics analyses reveals the effects of nano-selenium on pak choi

Yanyan Wang
Peiheng Sun
Xiaofei Li
ResearchOpen Access02 Apr 2025
Scientific Reports

Volume: 15, P: 1-16
GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy

Yujia Wang
Yinshuang Li
Yanfang Xu
ResearchOpen Access08 Aug 2022
Cell Death & Disease

Volume: 13, P: 1-15
The landscape of cancer research and cancer care in China

The authors discuss how screening strategies, treatment approaches and precision oncology are evolving in China and outline trends and priorities in the drug development and regulatory landscape.

Zhihao Lu
Yang Chen
Lin Shen
Reviews12 Dec 2023
Nature Medicine

Volume: 29, P: 3022-3032
The microbial carbon pump and climate change

In this Review, Jiao, Robinson and colleagues examine recent advances related to the microbial carbon pump, exploring its role in the carbon cycle and climate change, and proposing future research directions and approaches to ocean negative carbon emissions.

Nianzhi Jiao
Tingwei Luo
Carol Robinson
Reviews15 Mar 2024
Nature Reviews Microbiology

Volume: 22, P: 408-419
Institutional structure and governance capability in universities: an empirical study from the perspectives of time, space, and quantity dimensions

Zhimin Luo
Ma Junfeng
Li Zilong
ResearchOpen Access13 Aug 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-17
Comparative efficacy of prophylactic protocols in reducing perioperative nausea and vomiting during video-assisted thoracoscopic radical resection of lung cancer

Weiguang Zhang
Zhimin Shen
Mingqiang Kang
ResearchOpen Access29 Apr 2024
Scientific Reports

Volume: 14, P: 1-11
The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals

Yanan Cao
Lin Li
Mengyao Wang
ResearchOpen Access30 Apr 2020
Cell Research

Volume: 30, P: 717-731
Single-cell sequencing reveals homogeneity and heterogeneity of the cytopathological mechanisms in different etiology-induced AKI

Zhimin Chen
Yinshuang Li
Yanfang Xu
ResearchOpen Access11 May 2023
Cell Death & Disease

Volume: 14, P: 1-17
STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway

Qiang Guo
Ximiao Chen
Xiaolei Zhang
ResearchOpen Access04 Jan 2021
Cell Death & Disease

Volume: 12, P: 1-14
Role of redox potential and reactive oxygen species in stress signaling

Victor Adler
Zhimin Yin
Ze'ev Ronai
Research04 Nov 1999
Oncogene

Volume: 18, P: 6104-6111
Effects of train speed and passenger capacity on the environmental vibration of viaduct and surrounding soil of suburban railways

Hongkai Wang
Dong Li
Futong Wang
ResearchOpen Access31 Oct 2024
Scientific Reports

Volume: 14, P: 1-14
Analysis of the potential regulatory mechanisms of female and latent genital tuberculosis affecting ovarian reserve function using untargeted metabolomics

Zhimin Wang
Xueyan Zhang
Xiujuan Chen
ResearchOpen Access25 Apr 2024
Scientific Reports

Volume: 14, P: 1-14
Inferential Emotion Tracking reveals impaired context-based emotion processing in individuals with high Autism Quotient scores

Jefferson Ortega
Zhimin Chen
David Whitney
ResearchOpen Access19 May 2023
Scientific Reports

Volume: 13, P: 1-13
Identification of a five genes prognosis signature for triple-negative breast cancer using multi-omics methods and bioinformatics analysis

Jiulong Ma
Chen Chen
Liqun Ren
Research26 Apr 2022
Cancer Gene Therapy

Volume: 29, P: 1578-1589
Highly accurate and large-scale collision cross sections prediction with graph neural networks

The collision cross section (CCS) values derived from ion mobility spectrometry (IMS) are a significant molecular property used for compound identification, however, accurate CCS prediction from molecular structure remains challenging. Here, the authors develop an accurate SigmaCCS approach based on graph neural networks using 3D conformers generated from SMILES strings to directly predict CCS values from molecular structures.

Renfeng Guo
Youjia Zhang
Zhimin Zhang
ResearchOpen Access04 Jul 2023
Communications Chemistry

Volume: 6, P: 1-10
Super-enhancer-driven SLCO4A1-AS1 is a new biomarker and a promising therapeutic target in glioblastoma

Yibo Wu
Fang Li
Mingzhi Han
ResearchOpen Access06 Jan 2025
Scientific Reports

Volume: 15, P: 1-20
Developmental potential of clinically discarded human embryos and associated chromosomal analysis

Guidong Yao
Jiawei Xu
Yingpu Sun
ResearchOpen Access05 Apr 2016
Scientific Reports

Volume: 6, P: 1-9
Impact of radiotherapy on second primary lung cancer incidence and survival in esophageal cancer survivors

Jieming Lu
Dinghang Chen
Mingqiang Kang
ResearchOpen Access31 Jul 2024
Scientific Reports

Volume: 14, P: 1-11
Omics-based construction of regulatory variants can be applied to help decipher pig liver-related traits

Regulatory genetic variants repertoire in pig liver was expanded using RNA-seq, H3K27ac ChIP-seq, and DNA sequencing. These genetic foundations facilitate the dissection of molecular mechanisms underlying complex traits.

Ziqi Ling
Jing Li
Lusheng Huang
ResearchOpen Access29 Mar 2024
Communications Biology

Volume: 7, P: 1-16
Chuanxiong Rhizoma regulates ferroptosis and the immune microenvironment in ischemic stroke through the JAK-STAT3 pathway

Qianxi Ge
Zhimin Wang
Yiran Chen
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-17
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma

Jiwei Wang
Anbin Chen
Bin Huang
ResearchOpen Access02 Sept 2023
Cell Death & Disease

Volume: 14, P: 1-13
Black Hydroxylated Titanium Dioxide Prepared via Ultrasonication with Enhanced Photocatalytic Activity

Chenyao Fan
Chao Chen
Zhiyu Wang
ResearchOpen Access02 Jul 2015
Scientific Reports

Volume: 5, P: 1-10
Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the receptor protein of CRL2^Prame complex

Wenjuan Zhang
Lihui Li
Lijun Jia
ResearchOpen Access27 Jan 2021
Cell Death & Differentiation

Volume: 28, P: 1926-1940
Pigment epithelium-derived factor attenuates myocardial fibrosis via inhibiting Endothelial-to-Mesenchymal Transition in rats with acute myocardial infarction

Hao Zhang
Hongliang Hui
Hongyan Dong
ResearchOpen Access07 Feb 2017
Scientific Reports

Volume: 7, P: 1-14
Systematic analyses identify the anti-fibrotic role of lncRNA TP53TG1 in IPF

Jian Sun
Yingying Guo
Haihai Liang
ResearchOpen Access04 Jun 2022
Cell Death & Disease

Volume: 13, P: 1-13
A molecular subtyping associated with the cGAS-STING pathway provides novel perspectives on the treatment of ulcerative colitis

Chen Wang
Xin Gao
Xiaolan Zhang
ResearchOpen Access03 Jun 2024
Scientific Reports

Volume: 14, P: 1-13
Author Correction: Studying the impact of marital status on diagnosis and survival prediction in pancreatic ductal carcinoma using machine learning methods

Qingquan Chen
Yiming Hu
Liuxia You
Amendments and CorrectionsOpen Access22 Mar 2024
Scientific Reports

Volume: 14, P: 1
Targeting SNRNP200-induced splicing dysregulation offers an immunotherapy opportunity for glycolytic triple-negative breast cancer

Wenxiao Yang
Luo Hong
Xin Hu
ResearchOpen Access17 Sept 2024
Cell Discovery

Volume: 10, P: 1-19
G-protein-coupled receptor GPR17 inhibits glioma development by increasing polycomb repressive complex 1-mediated ROS production

Huiqing Liu
Rui Xing
Ying Chen
ResearchOpen Access12 Jun 2021
Cell Death & Disease

Volume: 12, P: 1-14

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