Nature Search

SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape

A survey of SARS-CoV-2 RBD antibodies identifies those with activity against diverse SARS-CoV-2 variants and SARS-related coronaviruses, highlighting epitopes and features to prioritize in antibody and vaccine development.

Tyler N. Starr
Nadine Czudnochowski
Gyorgy Snell
Research14 Jul 2021
Nature

Volume: 597, P: 97-102
Nanosensitizer-mediated augmentation of sonodynamic therapy efficacy and antitumor immunity

The dense stroma of desmoplastic tumor limits nanotherapeutic penetration and hampers the antitumor immune response. Here the authors use tin monosulfide nanoparticles as nano-sonosensitizers to overcome the stromal barrier in triple negative breast cancer and improve the efficacy of sonodynamic therapy and boost antitumor immunity.

Yongjiang Li
Wei Chen
Wei Tao
ResearchOpen Access01 Nov 2023
Nature Communications

Volume: 14, P: 1-17
Cold seeps are potential hotspots of deep-sea nitrogen loss driven by microorganisms across 21 phyla

Little is known about nitrogen loss processes in deep-sea cold seeps. Here, the authors report that cold seeps are potential hotspots of nitrogen loss, revealing high rates and a diverse range of nitrogen loss genes across multiple microbial phyla.

Qiuyun Jiang
Lei Cao
Xiyang Dong
ResearchOpen Access14 Feb 2025
Nature Communications

Volume: 16, P: 1-16
Topological perturbations on resilience of the world trade competition network

Zhao Li
Ren Zhuoming
Weng Tongfeng
ResearchOpen Access26 Apr 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-9
Imprinting of serum neutralizing antibodies by Wuhan-1 mRNA vaccines

In mouse experiments and in clinical trials in humans, boosting with Omicron-specific mRNA following immunization with Wuhan-1 spike mRNA results in immune responses focused on conserved rather than variant-specific epitopes.

Chieh-Yu Liang
Saravanan Raju
Michael S. Diamond
Research15 May 2024
Nature

Volume: 630, P: 950-960
Germinal centre-driven maturation of B cell response to mRNA vaccination

Sequencing of B cell receptors and expression of the corresponding monoclonal antibodies is used to characterize the evolution of the long-term B cell response to SARS-CoV-2 mRNA vaccination.

Wooseob Kim
Julian Q. Zhou
Ali H. Ellebedy
Research15 Feb 2022
Nature

Volume: 604, P: 141-145
In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains

Experiments in mouse and hamster models show that monoclonal antibody combinations, using antibodies that correspond to products in clinical development, largely retain their efficacy in protecting against currently prevailing variant strains of SARS-CoV-2.

Rita E. Chen
Emma S. Winkler
Michael S. Diamond
Research21 Jun 2021
Nature

Volume: 596, P: 103-108
SARS-CoV-2 Omicron boosting induces de novo B cell response in humans

COVID-19 booster immunizations aimed at spike protein from new SARS-CoV-2 variants induce robust germinal centre B cell responses against the original spike protein, as well as de novo B cell responses against the variant spike protein.

Wafaa B. Alsoussi
Sameer Kumar Malladi
Ali H. Ellebedy
Research03 Apr 2023
Nature

Volume: 617, P: 592-598
Broad sarbecovirus neutralization by a human monoclonal antibody

The human monoclonal antibody S2X259 cross-reacts with spike proteins from all clades of sarbecovirus, and provides prophylactic and therapeutic protection in vivo against parental SARS-CoV-2 and emerging variants of concern.

M. Alejandra Tortorici
Nadine Czudnochowski
Matteo Samuele Pizzuto
Research19 Jul 2021
Nature

Volume: 597, P: 103-108
Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells

Clostridium difficile toxin A utilizes host sulfated glycosaminoglycans and low-density lipoprotein receptor for host cell entry and intoxication.

Liang Tao
Songhai Tian
Min Dong
Research03 Jun 2019
Nature Microbiology

Volume: 4, P: 1760-1769
Defining the risk of SARS-CoV-2 variants on immune protection

The SARS-CoV-2 Assessment of Viral Evolution (SAVE) programme provides a real-time risk assessment of SARS-CoV-2 variants with the potential to affect transmission, virulence and resistance to infection- and vaccine-induced immunity.

Marciela M. DeGrace
Elodie Ghedin
Mehul S. Suthar
Reviews31 Mar 2022
Nature

Volume: 605, P: 640-652
A comprehensive genomic catalog from global cold seeps

Yingchun Han
Chuwen Zhang
Xiyang Dong
ResearchOpen Access08 Sept 2023
Scientific Data

Volume: 10, P: 1-10
Comparative Effectiveness of Di'ao Xin Xue Kang Capsule and Compound Danshen Tablet in Patients With Symptomatic Chronic Stable Angina

Yanan Yu
Siyuan Hu
Yongyan Wang
ResearchOpen Access14 Nov 2014
Scientific Reports

Volume: 4, P: 1-8
Preferential loss of gut-homing α4β7 CD4⁺ T cells and their circulating functional subsets in acute HIV-1 infection

Xiaofan Lu
Zhen Li
Hao Wu
Research17 Aug 2015
Cellular & Molecular Immunology

Volume: 13, P: 776-784
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity

Wenwei Luo
Jingyan Li
Zhuoming Li
ResearchOpen Access26 Jul 2021
Cell Death & Disease

Volume: 12, P: 1-13
Acoustic properties of vowel production in Mandarin-speaking patients with post-stroke dysarthria

Zhiwei Mou
Zhuoming Chen
Li Xu
ResearchOpen Access21 Sept 2018
Scientific Reports

Volume: 8, P: 1-12
Sorting nexin 3 induces heart failure via promoting retromer-dependent nuclear trafficking of STAT3

Jing Lu
Suowen Xu
Peiqing Liu
Research04 May 2021
Cell Death & Differentiation

Volume: 28, P: 2871-2887

Search

SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape

Nanosensitizer-mediated augmentation of sonodynamic therapy efficacy and antitumor immunity

Cold seeps are potential hotspots of deep-sea nitrogen loss driven by microorganisms across 21 phyla

Topological perturbations on resilience of the world trade competition network

Imprinting of serum neutralizing antibodies by Wuhan-1 mRNA vaccines

Germinal centre-driven maturation of B cell response to mRNA vaccination

In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains

SARS-CoV-2 Omicron boosting induces de novo B cell response in humans

Broad sarbecovirus neutralization by a human monoclonal antibody

Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells

Defining the risk of SARS-CoV-2 variants on immune protection

A comprehensive genomic catalog from global cold seeps

Comparative Effectiveness of Di'ao Xin Xue Kang Capsule and Compound Danshen Tablet in Patients With Symptomatic Chronic Stable Angina

Preferential loss of gut-homing α4β7 CD4⁺ T cells and their circulating functional subsets in acute HIV-1 infection

HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity

Acoustic properties of vowel production in Mandarin-speaking patients with post-stroke dysarthria

Sorting nexin 3 induces heart failure via promoting retromer-dependent nuclear trafficking of STAT3

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