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Reverse chemical ecology: specific binding of muscone to odorant binding protein (MjavOBP3) reveals its role in scent-marking behavior in Sunda pangolins.
Hernandez-Trejo, Ciuparu, and Garcia da Silva et al. report that the piriform-to-olfactory bulb feedback in the mouse carries multimodal identity and reward contingency signals, which are re-formatted within seconds, according to behavioral context.
Norepinephrine play critical roles in regulating olfactory behaviors, but the precise circuits and mechanisms underlying this function remain unclear. Here, authors show how LC–aPC/OB NAergic pathway regulate odor processing and olfactory discrimination.
Local manipulation of orexin signaling reveals that the anteromedial domain of the OT is the crucial region that integrates odor information and metabolic signals and directs appropriate odor-guided feeding behavior according to metabolic status.
In mice, the endocannabinoid system inhibits glutamatergic signalling from the olfactory cortex to the main olfactory bulb after fasting, increasing the detection of food odours and, consequently, enhancing food consumption.
Learned odor discrimination and generalization are reflected in patterns of ensemble activity in anterior piriform cortex, where learned discrimination between two odors reduces the correlation between their induced patterns.