A field experiment shows that turning on the algorithmic feed on the social-media platform X in 2023 shifted political opinions to the right, whereas turning it off had no effect on political attitudes. The algorithmic feed led users to follow more right-leaning accounts, which they continued following when the algorithm was off.

In an experimental trial, a personalized mRNA vaccine was tested in 14 individuals with an aggressive form of breast cancer. It trained immune cells to target cancer-specific mutant proteins, inducing strong, lasting immunity. Ten participants remained disease-free. Analysis of relapses revealed resistance mechanisms, offering essential insights for future therapies.

An artificial-intelligence system uses clinical data, genetic information and literature searches to suggest diagnoses and provides the underlying reasoning.

Optical-amplifier devices that boost light signals are workhorses of modern technology, but shrinking them onto microchips requires impractically high power. An amplifier architecture has been developed that recycles its own ‘pump’ energy to achieve high performance at power levels ten times lower than those of previous designs, making low-power, chip-scale optical amplification practical.