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Acceleration of Respiration of Normal and Tumour Tissue by Thionine (Lauth's Violet)

Abstract

THE defective oxidation of carbohydrate by tumour tissue (Dickens and imer)1 causes experiments directed towards its restoration to be of interest. It is now known that at least two types of reagent are able to function as catalysts in increasing directly the oxygen consumption of body-cells: (a) certain reversibly oxidisable systems, particularly methylene blue2,3 and pyocyanine4 ; (6) the dinitrophenols, particularly dinitro-o-eresol, found by Dodds and Grevih5,6 to increase the respiration of surviving kidney and tumour tissue.

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References

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DICKENS, F. Acceleration of Respiration of Normal and Tumour Tissue by Thionine (Lauth's Violet). Nature 134, 382–383 (1934). https://doi.org/10.1038/134382b0

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