Abstract
THE hind limbs of a Hungarian frog are perfused with veratrine 1/50,000 in Ringer's solution. The liquid collected from the vein perfuses a second, similar Trendelenburg's preparation. Direct tetanic stimulation of the hind limbs of the first frog is followed, after a latent period of about 10 minutes, by an irregular contraction of the perfused muscles of the second frog. It is thus possible to demonstrate a humoral transmission of the contraction in the presence of veratrine.
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SZENT-GYÖRGYI, A., BACQ, Z. & GOFFART, M. A Humoral Transmission of Muscular Contraction in the Presence of Veratrine. Nature 143, 522 (1939). https://doi.org/10.1038/143522a0
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DOI: https://doi.org/10.1038/143522a0
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