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Autocatalysis and Blood Coagulation

Abstract

THE autocatalytic behaviour of blood coagulation is thought, by several authors, to be due to the autocatalytic formation of thrombin from its precursor prothrombin1. So far, thrombin seems similar to the enzymes studied by Northrop and co-workers2.

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References

  1. Gratia, A. and Fredericq, P., C.R. Soc. Biol., 126, 906 (1937).

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  2. Compare Northrop, J. H., J. Gen. Physiol., 21, 335 (1938).

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  3. Fischer, A., NATURE, 135, 1075 (1935).

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ASTRUP, T. Autocatalysis and Blood Coagulation. Nature 144, 76 (1939). https://doi.org/10.1038/144076a0

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