Abstract
DURING the progress of an investigation into the effects of various toxic drugs on the cytology and histology of the liver, it was found that after a single injection of a sub-lethal dose of chloroform (0·5 c.c. of 10 per cent solution of chloroform in liquid paraffin) into male rats, the Scharlach R stainable fat in the liver appeared and disappeared in a rhythmic fashion.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Goldberg, Sylvia, personal communication.
Heyd, C. G., J. Amer. Med. Assoc., 121, 736 (1943).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
KNOCKER, P., MANDELSTAM, J. Rhythmic Changes in the Rat Produced by a Single Injection of Chloroform. Nature 154, 148–149 (1944). https://doi.org/10.1038/154148b0
Issue date:
DOI: https://doi.org/10.1038/154148b0
