Abstract
ANEURIN disulphide1, formed by opening of the thiazole ring and oxidation to the—S—S—form, does not give the thiochrome reaction, unless suitably reduced by cysteine; it was reported to have some 60 per cent of the biological activity of aneurin, when given orally to animals. I have found in catatorulin tests, by methods previously described2, with the deficient pigeon brain that it is at least as active as aneurin (Table 1).
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References
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PETERS, R. Catatorulin Effect of Aneurin Disulphide. Nature 158, 707 (1946). https://doi.org/10.1038/158707a0
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DOI: https://doi.org/10.1038/158707a0
