Abstract
Adrenalectomy causes a decrease in the arginase activity of the liver1,2 and lactating mammary gland2 in the rat. These findings, together with complementary observations on the abilities of various adrenal cortex steroids to restore the depleted tissue arginase levels after adrenalectomy1,2, are of great interest in view of the fact that it is now believed3 that certain cortical hormones promote gluconeo-genesis from protein, a process entailing deamination of amino-acids and the excretion of the nitrogen as urea through the ornithine cycle which, of course, involves the action of arginase.
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FOLLEY, S., GBEENBAUM, A. Decrease in the Arginase of the Liver and Mammary Gland in Adrenalectomized Lactating Rats as Compared with Pair-fed Controls. Nature 160, 364 (1947). https://doi.org/10.1038/160364a0
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DOI: https://doi.org/10.1038/160364a0
