Abstract
In a recent note1, we described the purification of renin by means of a fractional precipitation with protein-precipitating agents (sulphosalicylic acid and tungstic acid). In order to test the adaptability of this method, we have investigated the fractional precipitation of blood serum using electrophoresis (Tiselius) for analysing the composition of the products isolated. The most important of the results so far obtained is that it is possible, if we choose the right conditions and suitable precipitating agents, to perform the fractionation with a high degree of selectivity.
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References
Astrup, T., and Birch-Andersen, A., [Nature, 160, 570 (1947)].
Rinderknecht, H., Noble, R. L., and Williams, P. C., Biochem. J., 33, 381 (1939).
Rimington, C., and Rowlands, I. W., Biochem. J., 35, 736 (1941).
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ASTRUP, T., BIRCH-ANDERSEN, A. Fractional Precipitation of Serum Proteins. Nature 160, 637 (1947). https://doi.org/10.1038/160637a0
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DOI: https://doi.org/10.1038/160637a0
