Utilization of Wheat Bran for Streptomycin Production by S. griseus

Abstract

THE study of the nutritive requirements of Streptomyces griseus has assumed great importance on account of the remarkable activity of streptomycin against a number of bacterial infections. A number of media in which successful antibiotic production takes place have been recorded in the literature^1–5. During the course of investigations on streptomycin production, aqueous extracts of wheat bran were found to give encouraging results; the methods of preparation and composition of the extract are described elsewhere⁶. By the procedure employed, about 4,000 ml. of the extract with about 3 per cent total solid content can be prepared from 1,000 gm. of bran.