Terramycin and Spironema duttoni Infections

Abstract

IN the course of experiments with terramycin upon various laboratory infections, we have found that the drug has a powerful effect on Spironema duttoni in mice. The animals were inoculated intraperitoneally with a suspension of blood from a heavily infected mouse. Untreated mice usually died in three to six days; occasionally a mouse survived and the infection pursued a relapsing course. Treatment with terramycin was given on the day after infection, either by subcutaneous injection or by stomach tube.