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‘Parathion’ and Ultra-violet Light

Abstract

PURE ‘Parathion’ is not at present considered to be an inhibitor of cholinesterase in vitro1–3. It is probable that those who first reported4–6 to the contrary were using samples contaminated with one or more of the following: O-S-diethyl p-nitrophenyl thiophosphate, diethyl S-p-nitrophenyl thiophosphate and diethyl p-nitrophenyl phosphate (‘Paraoxon’), all of which possess anticholinesterase activity in vitro2.

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References

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  2. Aldridge, W. N., and Barnes, J. M., Nature, 169, 345 (1952).

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  3. Stegwee, D., Biochim. Biophys. Acta, 8, 187 (1952).

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PAYTON, J. ‘Parathion’ and Ultra-violet Light. Nature 171, 355–356 (1953). https://doi.org/10.1038/171355a0

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