Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Sulphur-containing Amino-acids of Nisin

Nature volume 171, page 606 (1953)Cite this article

Abstract

IN a recent publication1, we reported that a preparation of the antibiotic nisin could be resolved into at least four active polypeptides, which all yielded on hydrolysis two sulphur-containing amino-acids not normally found in proteins. These amino-acids behaved like lanthionine and cystathionine on two-dimensional paper chromatograms and treatment of a mixture of them with Kaney nickel yielded two substances which behaved like alanine and α-amino-n-butyric acid.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on SpringerLink
  • Instant access to the full article PDF.

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Berridge, N. J., Newton, G. G. F., and Abraham, E. P., Biochem. J., 52, 529 (1952).

    Article  CAS  Google Scholar 

  2. Stein, W. H., and Moore, S., J. Biol. Chem., 192, 663 (1951).

    PubMed  Google Scholar 

  3. Chinard, F. P., J. Biol. Chem., 199, 91 (1952).

    CAS  Google Scholar 

  4. Lewis, J. C., and Alderton, G., Abst. Amer. Chem. Soc., 114th meeting 61–62 C (1948).

  5. Lewis, J. C., and Snell, N. S., J. Amer. Chem. Soc., 73, 4812 (1951).

    Article  CAS  Google Scholar 

  6. Alderton, G., Abst. Amer. Chem. Soc., 123rd meeting, 31C (1953), J. Amer. Chem. Soc. (in the press).

  7. Ehrlich, J., Anderson, L. E., Coffey, G. L., and Gottlieb, D., Antibiotics and Chemotherapy, 2, 581 (1952).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Sir William Dunn School of Pathology, University of Oxford,

    G. G. F. NEWTON & E. P. ABRAHAM

  2. National Institute for Research in Dairying, University of Reading,

    N. J. BERRIDGE

Authors
  1. G. G. F. NEWTON
    View author publications

    Search author on:PubMed Google Scholar

  2. E. P. ABRAHAM
    View author publications

    Search author on:PubMed Google Scholar

  3. N. J. BERRIDGE
    View author publications

    Search author on:PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

NEWTON, G., ABRAHAM, E. & BERRIDGE, N. Sulphur-containing Amino-acids of Nisin. Nature 171, 606 (1953). https://doi.org/10.1038/171606a0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/171606a0

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing