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Induction of Ovarian Tumours with 9:10-Dimethyl-1 : 2-Benzanthracene

Abstract

MAMMARY carcinoma can be readily induced in certain strains of mice by treatment with 20-methylcholanthrene. In the course of experiments intended to investigate whether other members of the same group of carcinogenic hydrocarbons are also effective on the breast, an incidental finding has been made that treatment with 9 : 10-dimethyl-1 : 2-benzanthracene leads to the appearance of ovarian tumours.

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References

  1. Orr, J. W., J. Path. Bact., 58, 589 (1946).

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MARCHANT, J., ORR, J. & WOODHOUSE, D. Induction of Ovarian Tumours with 9:10-Dimethyl-1 : 2-Benzanthracene. Nature 173, 307 (1954). https://doi.org/10.1038/173307a0

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