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Elution of Isoagglutinins adsorbed by Platelets

Abstract

THE existence of A, B, O and AB groups in thrombocytes, corresponding to these groups in red blood cells, has been reported1,2. The identity of the A and B antigens in platelets and red blood cells has been proved by: (1) platelet agglutination with antisera; (2) cross-adsorption of isoagglutinins with thrombocytes and erythrocytes; (3) inhibition of isoagglutinins with saliva from secretors; and (4) neutralization of antisera with A- and B-group specific substances. Similar results of agglutination of platelets were reported by Ruggieri and Bolognesi3. Adsorption of A- and B-isoagglutinins with platelets was reported by Moureau and André4.

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References

  1. Gurevitch, J., and Nelken, D., Nature, 173, 356 (1954).

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  2. Gurevitch, J., and Nelken, D., J. Lab. and Clin. Med., 44, 562 (1954).

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  3. Ruggieri, P., and Bolognesi, G., Boll. Soc. Ital. Ematologia, 2, 127 (1954).

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  4. Moureau, P., and André, A., Vox Sanguinis, 4, 46 (1954); Nature, 174, 88 (1954).

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  5. Landsteiner, K., and Miller, C. P., J. Exp. Med., 42, 852 (1925).

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GUREVITCH, J., NELKEN, D. Elution of Isoagglutinins adsorbed by Platelets. Nature 175, 822 (1955). https://doi.org/10.1038/175822a0

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