Abstract
IT is well known that artefacts and serious distortion can be caused during paper chromatography if acids are present in the solution being chromatographed, and that they can be eliminated by initial electrolytic desalting. In a recent communication1, Acland confirmed that trichloracetic acid can be “largely” removed by desalting the solution electrolytically ; as an example, he showed that the chromatographic picture from a mixture of thyroxine and trichloracetic acid was very distorted, whereas that from a mixture of thyroxine and ‘desalted’ trichloracetic acid was relatively undistorted.
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References
Acland, J. D., Nature, 176, 694 (1955).
Bowden, C. H., Maclagen, N. F., and Wilkinson, J. H., Biochem. J., 59, 93 (1955).
Smith, I., Stevens, B. J., and Jepson, J. B., Proc. Biochem. Soc., November meeting, Biochem. J. (in the press).
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JEPSON, J., SMITH, I. Destruction of Thyroxine by Electrolytic Desalting. Nature 177, 84 (1956). https://doi.org/10.1038/177084a0
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DOI: https://doi.org/10.1038/177084a0
