Abstract
LATE in 1954, I discovered two adult Filipino men unrelated to each other with a thalassæmia-like blood picture. Electrophoretic examination of hæmoglobin at pH. 8.6 and 6.0 revealed a major component of normal hæmoglobin and a minor component with electrophoretic mobility faster than normal hæmoglobin A; further work led to identification of the new fraction as hæoglobin H. Detailed studies on these patients will be published elsewhere.
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References
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Motulsky, Arno G., Paul, Milton H., and Durrum, E. L., Blood, 9, 897 (1954).
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MOTULSKY, A. Genetic and Hæmatological Significance of Hæmoglobin H. Nature 178, 1055–1056 (1956). https://doi.org/10.1038/1781055b0
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DOI: https://doi.org/10.1038/1781055b0
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