Abstract
Horsfall and Smithies1 have recently reported evidence for the genetic control of some human serum β-globulins. Two autosomal alleles with no dominance (βc and βD) were proposed to account for the variable presence of the β-globulins C and D, demonstrated by two-dimensional starch-gel electrophoresis2, in sera from Australian aborigines and Negroes3. No evidence was available from previous studies (made for the most part by one-dimensional starch-gel electrophoresis) for the presence of β-globulin D in the sera of several hundred Canadians.
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References
Horsfall, W. R., and Smithies, O., Science (in the press).
Smithies, O., and Poulik, M. D., Nature, 177, 1033 (1956).
Smithies, O., Nature, 180, 1482 (1957).
Smithies, O., and Walker, N. F., Nature, 178, 694 (1956).
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SMITHIES, O. Third Allele at the Serum β-Globulin Locus in Humans. Nature 181, 1203–1204 (1958). https://doi.org/10.1038/1811203b0
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DOI: https://doi.org/10.1038/1811203b0
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