Abstract
RECENTLY, Lwoff and Lwoff1 showed that the development of the virus of poliomyelitis in KB cell cultures (cell strain from a human epidermoid carcinoma—H. Eagle), while occurring ‘normally’ at 37° C., is at least partially blocked at 39° C., only about 0.2–0.4 per cent of the virus at 37° C. being produced. They found the blockage to be reversible and considered that it occurred in a “late stage of the vegetative phase”.
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References
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Cartwright, S. F., and Thorne, H. V., J. Gen. Microbiol. (in the press).
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SHARPE, H. Effect of Temperature on the Multiplication of Foot-and-Mouth Disease Virus in Suspensions of Kidney Cells of the Pig. Nature 182, 1803–1805 (1958). https://doi.org/10.1038/1821803a0
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DOI: https://doi.org/10.1038/1821803a0
