Abstract
MEDIAN lethal doses of the plant pyrrolizidine alkaloids, heliotrine and lasiocarpine, have been determined by Bull et al.1. Deaths occurred from hepatotoxic effects except in some female rats given heliotrine.
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References
Bull, L. B., Dick, A. T., and McKenzie, J. S., J. Path. Bact., 75, 17 (1958).
Mogey, G. A., Trevan, J. W., and Young, P. A., Analyst, 74, 577 (1949).
Paton, W. D. M., and Zaimis, E. J., Brit. J. Pharmacol., 4, 381 (1949).
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GALLAGHER, C., KOCH, J. Action of Pyrrolizidine Alkaloids on the Neuro-Muscular Junction. Nature 183, 1124–1125 (1959). https://doi.org/10.1038/1831124a0
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DOI: https://doi.org/10.1038/1831124a0
