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Neuronal Dye-Sorption as a Histochemical Indicator of Nervous Activity

Nature volume 183, pages 1337–1338 (1959)Cite this article

Abstract

PROTEIN extracts from electrically stimulated nervous tissue have been reported to undergo changes resembling those of reversible denaturation1. Denaturation of protein, however, enhances dye-protein interaction2. It was postulated, therefore, that excitation of nervous tissue could be demonstrated histochemically3.

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References

  1. Ungar, G., J. de Physiol., 49, 1235 (1957). Ungar, G., et al., J. Gen. Physiol., 40, 635 (1957). Ungar, G., and Romano, D. V., Proc. Soc. Exp. Biol. and Med., 97, 324 (1958).

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  3. Fischer, R., paper presented at the meeting of the Ohio Valley Section of the Soc. Bxp. Biol. Med., Columbus, Ohio, Nov. 1, 1958 (in the press).

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Authors and Affiliations

  1. Research Division, Columbus Psychiatric Institute and Hospital, Ohio State University College of Medicine, Columbus

    ROLAND FISCHER & WOLFGANG ZEMAN

Authors
  1. ROLAND FISCHER
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  2. WOLFGANG ZEMAN
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FISCHER, R., ZEMAN, W. Neuronal Dye-Sorption as a Histochemical Indicator of Nervous Activity. Nature 183, 1337–1338 (1959). https://doi.org/10.1038/1831337a0

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