Abstract
ESCULETIN was found in an extract of plant tissue which contained caffeic acid. The esculetin was not a natural product but was formed from caffeic acid during the paper-chromatographic purification procedures. This conversion was confirmed by two-dimensional chromatography of authentic caffeic acid.
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References
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Undenfriend, S., Clark, C. T., Axelrod, J., and Brodie, B. B., J. Biol. Chem., 208, 731 (1958).
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BUTLER, W., SIEGELMAN, H. Conversion of Caffeic Acid to Esculetin during Paper Chromatography. Nature 183, 1813–1814 (1959). https://doi.org/10.1038/1831813a0
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DOI: https://doi.org/10.1038/1831813a0
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