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Inactivation of Isoniazid by Peroxidase

Nature volume 183, page 681 (1959)Cite this article

Abstract

INVESTIGATIONS on enzymes of Mycobacteria reported from this laboratory1 and elsewhere2,3 have shown the importance of cellular peroxidase for the activity of isoniazid. Results of an extension of these studies bearing on the effect of peroxidase on the tuberculostatic activity of isoniazid form the basis of the present communication.

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References

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Author notes

  1. M. O. TIRUNARAYANAN & W. A. VISCHER

    Present address: c/o J. R. Geigy S.A., Basle, Switzerland

Authors and Affiliations

  1. Medical Section, Schweiz. Forschungsinstitut für Tuberkulose, Davos

    M. O. TIRUNARAYANAN & W. A. VISCHER

Authors
  1. M. O. TIRUNARAYANAN
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  2. W. A. VISCHER
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TIRUNARAYANAN, M., VISCHER, W. Inactivation of Isoniazid by Peroxidase. Nature 183, 681 (1959). https://doi.org/10.1038/183681a0

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