Abstract
A CONNEXION has previously been demonstrated between the activation of copper-enzyme catalysis and the production of tanned lipoprotein surface membranes1. These same membranes, under various experimental conditions, were found to be nonadhesive2, and since tumour cell surfaces display this property3, it suggested the possibility that cellular adhesion may depend on the integrity of a proportion of the protein moiety of the lipoprotein complex of the surface membrane.
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References
Jones, B. M., Proc. Roy. Soc., B, 149, 263 (1958).
Jones, B. M., Symposium (1959), The Cell Surface, Proc. Roy. Phys. Soc. Edin. (to be published).
Ambrose, E. J., Nature, 182, 1419 (1958).
Dennell, R., and Malek, S. R. A., Proc. Roy. Soc., B, 144, 545 (1956).
Louis, C. J., Brit. J. Cancer, 12, 537 (1958).
Fitzpatrick, T. B., Becker, S. W., Lerner, A. B., and Montgomery, H., Science, 112, 223 (1950).
Dawson, C. R., and Tarpley, W. B., ‘The Enzymes’, 2, Pt. 1 (New York, Acad. Press, 1951).
Wynne, E. S., ‘Pigment Cell Biology’, 432, edit. Gordon, M. (New York, Acad. Press, 1959).
Grant, W. C., and Krantz, J. C., Cancer Res., 2, 833 (1942).
Slater, E. C., ‘Adv. Enzymol.’, 20, 147 (1958).
More, T., Nature, 184, 607 (1959).
Williams-Ashman, H. G., Cassman, M., and Klavins, M., Nature, 184, 427 (1959).
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JONES, B. Inhibition of Rous I Sarcoma Metastases by a Copper-Catalyst Blocking Agent. Nature 184, 1963–1964 (1959). https://doi.org/10.1038/1841963b0
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DOI: https://doi.org/10.1038/1841963b0
