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Effect of Iron and Zinc on Nucleic Acid and Protein Synthesis in Mycobacterium smegmatis

Abstract

WE HAVE observed1 that some cultures of Mycobacterium smegmatis on modified Proskauer and Beck medium2 stopped growing, and the pellicle sank before the usual yield of cells had been obtained. After growth had stopped, the bacilli in these cultures were very elongated and contained a low level of deoxyribonucleic acid (expressed on a protein nitrogen basis), compared with normal cultures of the same age.1

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References

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WINDER, F., DENNENY, J. Effect of Iron and Zinc on Nucleic Acid and Protein Synthesis in Mycobacterium smegmatis . Nature 184, 742–743 (1959). https://doi.org/10.1038/184742a0

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