Abstract
IT has been shown that acetone extracts of freeze-dried ox spleen are capable of stimulating hypodynamic papillary muscle1. Evidence has been reported recently2 which suggests that the cardioactivity cannot be explained in terms of choline or its esters, histamine, 5-hydroxytryptamine, adrenaline or noradrenaline. Further experiments reported below confirm the absence of catecholamines in an active extract.
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References
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COBBIN, L., THORP, R. Absence of Catecholamines in Cardioactive Acetone Extracts of Ox Spleen. Nature 186, 473–474 (1960). https://doi.org/10.1038/186473b0
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DOI: https://doi.org/10.1038/186473b0
