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Delayed Hypersensitivity to Homologous γ-Globulin in the Guinea Pig

Nature volume 189, pages 586–587 (1961)Cite this article

Abstract

THE existence in the rabbit of genetically determined antigenic differences (‘allotypes’) among homologous γ-globulins has been described by Oudin, who succeeded in preparing precipitating antisera against them after prolonged immunization with specific immune precipitates in adjuvants1. Considerable work has been done in an attempt to define the number of distinct serological groups and the number of genes controlling them in the rabbit2. The allotypic groups have been reported to be located on fragments I and II (as defined by R. R. Porter) of γ-globulin digested with papain3.

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References

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Authors and Affiliations

  1. Department of Pathology, New York University College of Medicine,

    B. BENACERRAF

  2. Department of Experimental Pathology, University of Birmingham, Birmingham, 15

    P. G. H. GELL

Authors
  1. B. BENACERRAF
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  2. P. G. H. GELL
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BENACERRAF, B., GELL, P. Delayed Hypersensitivity to Homologous γ-Globulin in the Guinea Pig. Nature 189, 586–587 (1961). https://doi.org/10.1038/189586b0

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