Abstract
AMYLOBARBITONE (5-ethyl-5-(3-methylbutyl) barbituric acid) fed to dogs in doses of 45 mgm. per kgm. has been shown to produce 5-ethyl-5-(3-hydroxy-3-methylbutyl) barbituric acid as the main metabolite, about 67 per cent of the original dose being excreted in this form1.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Maynert, E. W., Dawson, J. M., and Washburn, E., J. Biol. Chem., 195, 397 (1952).
Markham, R., and Smith, J. D., Nature, 163, 250 (1949).
Jackson, J. V., Chromatographic and Electrophoretic Techniques, edit. by Smith, Ivor, second ed., 1, 379 (Heinemann, London, 1960).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
JACKSON, J., MOSS, M. Identification of an Amylobarbitone Metabolite in Human Urine. Nature 192, 553–554 (1961). https://doi.org/10.1038/192553a0
Issue date:
DOI: https://doi.org/10.1038/192553a0
