Thromboplastic and Fibrinolytic Activity of the Arteriosclerotic Human Aorta

Abstract

Perlick¹ and Kirk² recently reported that the thromboplastic activity of intima and media from arteriosclerotic parts of the human aorta in general were lower than in normal sections. Kirk noted an especially low thromboplastic activity in ulcerated parts. Since arteriosclerotic lesions are usually supposed to be sites for thrombus formation these observations are of great interest. We present here an investigation on the thromboplastic and fibrinolytic activities of the layers of the arteriosclerotic human aorta.