Abstract
A HISTOCHEMICAL study, with the tetrazolium salt technique, of experimental cerebral œdema produced in cats by the local application of cold has shown a considerable increase of oxidation-reduction activity in reactive macroglia and microglia1. The fat-granule cells in the necrotic cortical lesion have furthermore been noted to display a response which differs constantly from that observed in the reactive astrocytes or the protein-carrying microglia in the œdematous white matter. In the present communication these findings are supplemented by histochemical observations on the reactive macrophage system elsewhere in the body as a result of a similarly produced necrotizing lesion.
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RUBINSTEIN, L., SMITH, B. Triphosphopyridine Nucleotide (TPN) Diaphorase and TPN-dependent Dehydrogenase Activity of Reactive Macrophages in Tissue Necrosis. Nature 193, 895 (1962). https://doi.org/10.1038/193895a0
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DOI: https://doi.org/10.1038/193895a0
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