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Immunological Properties of Electrophoretic Fractions of Human Growth Hormone

Nature volume 194, pages 491–492 (1962)Cite this article

Abstract

IN a previous investigation we showed that human growth hormone, prepared by Raben's method, presented on agar gel electrophoresis two distinct strongly staining components and a less-distinctive faster moving component1. Component 1 moved between β- and α-globulin, component 2 corresponded to α-2-globulin and component 3 to α-1-globulin. Similar findings have been reported with starch gel electrophoresis2,3. Our previous work confirmed the suspicion of Boucher4 and Hirschfeld et al.5 that the human growth hormone preparations, obtained by both Raben's and Li's methods, are contaminated with human albumin.

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References

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Authors and Affiliations

  1. Department of Pediatrics (Sharon-Hospital) and Rogoff Medical Research Institute, Department of Experimental Biology, Tel-Aviv University and Kupath Holim, Beilinson Medical Center, Petah-Tikva, Israel

    ZVI LARON & SARA ASSA

Authors
  1. ZVI LARON
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  2. SARA ASSA
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LARON, Z., ASSA, S. Immunological Properties of Electrophoretic Fractions of Human Growth Hormone. Nature 194, 491–492 (1962). https://doi.org/10.1038/194491a0

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