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Differential Characteristics in Uniform Strains of Mice

Abstract

THE pharmacological sensitivities of uniform mouse strains determined in specified conditions show clearly defined differential characteristics. The comparison is made in Fig. 1 for the same mouse strains between their approximate ED50 convulsive responses to doses of insulin, and their approximate LD50 to histamine. The colour density of the histogram is relative to the colour of the mouse strain.

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References

  1. Brown, A. M., J. Pharm. Pharmacol., 13, 670, 679 (1961).

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BROWN, A. Differential Characteristics in Uniform Strains of Mice. Nature 195, 204–205 (1962). https://doi.org/10.1038/195204a0

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