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Localized Areas of High Alkaline Phosphatase Activity in Endothelium of Arteries

Nature volume 195, pages 611–612 (1962)Cite this article

Abstract

THE earliest reports of histochemical reactions for phosphatases in the alkaline pH-range described activity in the endothelium of capillaries, “sometimes” in the endothelium of “blood vessels” and in the adventitia of medium-sized arterioles1–3. Differences in the activity of this enzyme in capillaries of various organs were noted. Since then, no specific localization of alkaline phosphatase activity has been described in the vascular tree4–6. The purpose of the present communication is to report the presence of intense alkaline phosphatase activity localized in the endothelium of small arteries and arterioles at their origin from larger vessels.

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Authors and Affiliations

  1. Neurological Unit, Boston City Hospital, and the Department of Neurology, Harvard Medical School, Boston, Mass.

    FLAVIU C. A. ROMANUL & ROGER G. BANNISTER

Authors
  1. FLAVIU C. A. ROMANUL
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  2. ROGER G. BANNISTER
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ROMANUL, F., BANNISTER, R. Localized Areas of High Alkaline Phosphatase Activity in Endothelium of Arteries. Nature 195, 611–612 (1962). https://doi.org/10.1038/195611a0

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