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Effect of Oleic Acid on the Mobility of Human Red Cells, and its Effect on Human Serum Protein Fractions

Abstract

THE higher fatty acids (C-18 acids such as oleic, ricinoleic, arachidonic, etc.) exist both in the adeno-carcinomas of the C3H mouse1 and in at least some human tumours2. They also occur in normal mouse and human tissues3, where they are combined, somewhat like the fatty acids in tumours, with lipid and protein inhibitors about which little is known. This communication is concerned with the question whether oleic acid (taken as an example of the higher fatty acids) affects the electrical mobility of human red cells (A, below), and whether it interacts with human serum protein fractions.

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References

  1. Ponder, E., and Ponder, R. V., Nature, 189, 643 (1961).

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  2. Ponder, E., and Ponder, R. V., Nature, 193, 1300 (1962).

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  3. Ponder, E., and Ponder, R. V., Nature, 184, 819 (1959).

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PONDER, E., PONDER, R. Effect of Oleic Acid on the Mobility of Human Red Cells, and its Effect on Human Serum Protein Fractions. Nature 197, 178–179 (1963). https://doi.org/10.1038/197178a0

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