Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Vitamin B12 in the Serum of the Rhesus Monkey

Abstract

MOST investigations of the physiology of vitamin B12 have been carried out in man or laboratory animals other than the sub-human primates. Indeed, it has been specifically noted that vitamin B12 deficiency has not been produced experimentally in monkeys1–3, and those macrocytic anæmias which have been induced are known to respond to treatment with folic acid (sometimes in association with ascorbic acid) but not to vitamin B12 (ref. 4).

This is a preview of subscription content, access via your institution

Access options

Buy this article

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Ruch, T. C., Diseases of Laboratory Primates (Saunders, Philadelphia, 1959).

    Google Scholar 

  2. Smith, E. L., Vitamin B12 (Methuen, London, 1960)

    Google Scholar 

  3. Innes, J. R. M., and Saunders, L. Z., Comparative Neuropathology (Academic Press, New York, 1962).

    Google Scholar 

  4. Sundberg, R. D., Schaer, F., and May, C. D., Blood, 7, 1143 (1952).

    CAS  PubMed  Google Scholar 

  5. Shinton, N. K., Clin. Sci., 18, 389 (1959).

    CAS  PubMed  Google Scholar 

  6. Ross, G. I. M., J. Clin. Path., 5, 250 (1952).

    Article  CAS  Google Scholar 

  7. Wilson, H. E., and Pitney, W. R., J. Lab. Clin. Med., 45, 590 (1955).

    CAS  PubMed  Google Scholar 

  8. Das Gupta, C. R., Chatterjea, J. B., Ghosh, S. K., and Banerjee, D. K., Bull. Calcutta Sch. Trop. Med., 3 (1955).

  9. Banerjee, D. K., and Chatterjea, J. B., Brit. Med. J., ii, 992 (1960).

  10. Smith, A. D. M., Brit. Med. J., i, 1655 (1962).

  11. Lillie, R. J., Olsen, M. W., and Bird, H. R., Proc. Soc. Exp. Biol. N.Y., 72, 598 (1949).

    Article  CAS  Google Scholar 

  12. Olcese, O., Couch, J. R., Quisenberry, J. H., and Pearson, P. B., J. Nutrit., 41, 423 (1950).

    CAS  PubMed  Google Scholar 

  13. Rulon, O., Proc. Soc. Exp. Biol. N.Y., 108, 380 (1961).

    Article  CAS  Google Scholar 

  14. Chow, B. F., Okuda, K., and McCollum, E. B., J. Nutrit., 74, 319 (1961).

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

KROHN, P., OXNARD, C. & CHALMERS, J. Vitamin B12 in the Serum of the Rhesus Monkey. Nature 197, 186 (1963). https://doi.org/10.1038/197186a0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/197186a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing