Abstract
THE aromatic ether fraction of oil of nutmeg has been previously shown1 to consist of eugenol (Ia), isoeugenol (IIa), safrole (Ic) and myristicin (Id). Vacuum distillation yields a fraction (b.p. 109°–112°/1 mm mercury; 60 g from 1 kg of ‘W.I.’ oil of nutmeg (George Lueders and Co.)) which consisted of a substance heretofore accepted both chemically1,2 and pharmacologically3 as the single compound, myristicin (Id). 
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References
Power, F. B., and Salway, A. H., J. Chem. Soc., 91, 2037 (1907).
Salway, A. H., J. Chem. Soc., 1204 (1909). Trikojus, V. M., and White, D. E., ibid., 436 (1949).
Truitt, jun., E. B., Calloway, III., E., Braude, M. C., and Krantz, jun., J. C., J. Neuropsychiat., 2, 205 (1961).
Naves, Y. R., and Ardisio, P., Bull. Soc. Chim. France, 1053 (1957).
Naves, Y. R., Ardisio, P., and Favre, C., Bull. Soc. Chim. France, 566 (1958).
Naves, Y. R., and Grampoloff, A. V., Bull. Soc. Chim. France, 1233 (1959).
Baxter, R. M., Fan, M. C., and Kandel, S. I., Canad. J. Chem., 40, 154 (1962).
Stahl, E., and Trennheuser, L., Arch. Pharm., 293/65, 826 (1960).
Hahn, G., and Wassmuth, H., Ber., 67, 696 (1934). Pearl, I. A., J. Amer. Chem. Soc., 70, 1747 (1948).
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SHULGIN, A. Composition of the Myristicin Fraction from Oil of Nutmeg. Nature 197, 379 (1963). https://doi.org/10.1038/197379a0
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DOI: https://doi.org/10.1038/197379a0
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