Abstract
HUMAN alkaline phosphatase of intestine but not of liver, bile, bone, lung, kidney and spleen is almost completely (78 per cent) inhibited by L-phenylalanine and is not so affected by D-phenylalanine.
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References
Fishman, W. H., Green, S., and Inglis, N. I., Abst. Amer. Chem. Soc., Inc. Washington, D.C. (March 23, 1962); Biochim. Biophys. Acta, 62, 363 (1962).
Shinowara, G. Y., Jones, L. M., and Reinhart, H. L., J. Biol. Chem., 142, 92 (1942).
Stolbach, L. L., Nisselbaum, J. S., and Fishman, W. H., Amer. J. Clin. Path., 29, 4 (1959).
Fishman, W. H., in Plasma Proteins, 2, 59, edit. by Putnam, F. (Academic Press Inc., New York, 1960).
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FISHMAN, W., GREEN, S. & INGLIS, N. L-Phenylalanine : an Organ Specific, Stereo-specific Inhibitor of Human Intestinal Alkaline Phosphatase. Nature 198, 685–686 (1963). https://doi.org/10.1038/198685b0
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DOI: https://doi.org/10.1038/198685b0
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