Abstract
GONADAL hormones markedly inhibit the growth, maturation and metabolism of lymphoid tissues1—effects which might be reflected in impaired immunological reactivity in animals treated with these hormones. We have examined this possibility in several experimental contexts.
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References
Kappas, A., and Palmer, R. H., Pharmacol. Rev., 15, 123 (1963).
Witebsky, E., Rose, N. R., Terplan, K., Paine, J. R., and Egan, R. W., J. Amer. Med. Assoc., 164, 1439 (1957).
Jones, H. E. H., and Roitt, I. M., Brit. J. Exp. Pathol., 42, 546 (1961).
Pearson, C. M., Proc. Soc. Exp. Biol. Med., 91, 95 (1956).
Mueller, M. N., and Kappas, A. (unpublished observations).
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KAPPAS, A., JONES, H. & ROITT, I. Effects of Steroid Sex Hormones on Immunological Phenomena. Nature 198, 902 (1963). https://doi.org/10.1038/198902a0
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DOI: https://doi.org/10.1038/198902a0
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