Use of a Combined Complement-fixing Antigen to detect Arthropod-borne Viral Infection

Abstract

IN an area where several arthropod-borne viruses are active, the examination by complement fixation of acute and convalescent human sera to detect possible infection with local agents may be tedious and time consuming. Sometimes the convalescent sera alone are screened and those that react with one or more antigens are then paired with the acute specimen and, retested.