Abstract
IN assessing the stability of the various possible linkages joining carbohydrates to amino-acid residues and in order to avoid base-catalysed acyl migration, we have synthesized N-(1,2 : 3,4-di-O-isopropylidene-D-galacturonyl)-glycine and its β-DL-phenylalanine analogue and examined their behaviour on hydrolysis. The syntheses were effected by using as condensing agents either dicyclohexylcarbodi-imide1, or tetraethylpyrophosphite2.
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AMIR, S., BARKER, S., FOSTER, A. et al. Stability of N-Glycuronyl Amino-acids. Nature 200, 166 (1963). https://doi.org/10.1038/200166a0
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DOI: https://doi.org/10.1038/200166a0
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